Synthesis, Crystal Structure and Biological Activity of 2-((2,2-Dimethyl-2,3-dihydrobenzofuran-7-yl)oxy)-N-(3-(furan-2-yl)-1-phe nyl-1H-pyrazol-5-yl)acetamide / Huo Jing-Qian ,Ma Liu-Yong ,Zhang Zhe ,Fan Zhi-Jin ,Zhang Jin-Lin ,Beryozkina Tetyana,Bakulev Vasiliy A. // CHINESE JOURNAL OF STRUCTURAL CHEMISTRY. - 2016. - V. 35, l. 7. - P. 1011-1018.

ISSN/EISSN:

0254-5861 / нет данных

Type:

Article

Abstract:

The title compound 2-((2,2-dimethyl-2,3-dihydrobenzofuran-7-yl)oxy)-N-(3-(furan-2-yl)-1-phe nyl-1H-pyrazol-5-yl) acetamide (C25H23N3O4, M-r = 429.46) has been synthesized, and its structure was characterized by H-1-NMR, C-13-NMR, H RMS, and single-crystal X-ray diffraction. The crystal belongs to the monoclinic system, space group P2(1)/c with a = 20.6205(18), b = 5.2930(5), c = 18.9282(17) angstrom, beta = 94.089(2)degrees, V = 2060.6(3) angstrom 3, Z = 4, D-c = 1.384 g/cm(3), mu(MoKa) = 0.71073 mm(-1), F(000) = 904, R = 0.0345 and wR = 0.0930. The intramolecular hydrogen bond at N(1)-H(1)center dot center dot center dot O(2), intermolecular weak interactions at O(3)center dot center dot center dot H(4) and weak pi-pi interactions connected the molecules to lead to one-dimensional tapes. Bioassay results indicated that the title compound had moderate herbicidal and fungicidal activities.

Author keywords:

benzofuran; pyrazole; furan; crystal structure; biological activity PYRAZOLE; ANTIBACTERIAL; INHIBITION

DOI:

10.14102/j.cnki.0254-5861.2011

Web of Science ID:

ISI:000385766200003

Соавторы в МНС:

Другие поля

Поле	Значение
Month	JUL
Publisher	CHINESE JOURNAL STRUCTURAL CHEMISTRY
Address	FUIJAN INST RES STRUCT MATTER, CHINESE ACAD SCIENCES, FUZHOU, FUJIAN 350002, PEOPLES R CHINA
Language	English
Keywords-Plus	PYRAZOLE; ANTIBACTERIAL; INHIBITION
Research-Areas	Chemistry; Crystallography
Web-of-Science-Categories	Chemistry, Inorganic \& Nuclear; Crystallography
Author-Email	fanzj@nankai.edu.cn zhangjinlin@hebau.edu.cn
Funding-Acknowledgement	National Natural Science Foundation of China {[}31171877]; International Science \& Technology Cooperation Program of China {[}2014DFR41030]
Funding-Text	This study was funded by the National Natural Science Foundation of China (31171877), and the International Science \& Technology Cooperation Program of China (No. 2014DFR41030)
Number-of-Cited-References	27
Usage-Count-Last-180-days	1
Usage-Count-Since-2013	2
Journal-ISO	Chin. J. Struct. Chem.
Doc-Delivery-Number	DZ3RH