Microwave-assisted synthesis and evaluation of antibacterial activity of novel 6-fluoroaryl-{[}1,2,4]triazolo{[}1,5-a]pyrimidines / Verbitskiy Egor V.,Baskakova Svetlana A.,Rasputin Nikolay A.,Gerasimova Natal'ya A.,Amineva Polina G.,Evstigneeva Natal'ya P.,Zil'berberg Natal'ya V.,Kungurov Nikolay V.,Kravchenko Marionella A.,Skornyakov Sergey N.,Rusinov Gennady L.,Chupakhin Oleg N.,Charushin Valery N. // ARKIVOC. - 2016. - V. , l. 5. - P. 268-278.

ISSN/EISSN:

1551-7004 / 1551-7012

Type:

Article

Abstract:

using the microwave-assisted Suzuki cross-coupling reaction from readily available 6-bromo-{[} 1,2,4] triazolo{[}1,5-a] pyrimidine. The antimicrobial activity of new compounds has been evaluated in vitro against Mycobacterium tuberculosis H(37)Rv and gram-negative (Neisseria gonorrhoeae ATCC 49226) bacteria.

Author keywords:

{[}1,2,4]triazolo{[}1,5-a]pyrimidines; Suzuki cross-coupling; microwave irradiation; antimycobacterial activity; anti-gonorrhea activity AGENTS; INHIBITORS; DESIGN; S-N(H)

DOI:

10.3998/ark.5550190.p009.731

Web of Science ID:

ISI:000385801100018

Соавторы в МНС:

Другие поля

Поле	Значение
Publisher	ARKAT USA INC
Address	C/O ALAN R KATRITZKY, UNIV FLORIDA, DEPT CHEMISTRY, PO BOX 117200, GAINESVILLE, FL 32611 USA
Language	English
EISSN	1551-7012
Keywords-Plus	AGENTS; INHIBITORS; DESIGN; S-N(H)
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
Author-Email	Verbitsky@ios.uran.ru
ResearcherID-Numbers	Baskakova, Svetlana/Q-6803-2016
Funding-Acknowledgement	Russian Science Foundation {[}15-13-00077]
Funding-Text	The research was financially supported by the Russian Science Foundation (Project No. 15-13-00077).
Number-of-Cited-References	26
Usage-Count-Last-180-days	4
Usage-Count-Since-2013	5
Journal-ISO	Arkivoc
Doc-Delivery-Number	DZ4BC