[Dependence of haemostasis system response from initial blood coagulation activity under total joints replacement]. / Antropova I.P., Iushkov B.G. // Rossiǐskii fiziologicheskiǐ zhurnal imeni I.M. Sechenova / Rossiǐskaia akademiia nauk. - 2012. - V. 98, l. 3. - P. 424-432.

ISSN:
08698139
Type:
Article
Abstract:
Effect of the initial state of the plasma hemostasis on the hemocoagulation changes after the total arthroplasty surgery was studied in 100 patients with osteoarthritis. Indicators of coagulation, fibrinolysis, and physiological anticoagulants were determined before and after completion of the surgery, at days 1, 3, 7, and 13-14 postoperatively. Increased coagulation activity befor surgery enhanced blood clotting within three days after the surgery. Enhanced consumption of physiological anticoagulants reduced the ability to recover their level a week after arthroplasty. The raised activity of the fibrinolysis inhibitor retained the effect during three postoperative days. Initial abnormalities in plasma hemostasis enhance blood coagulation dysfunction caused by surgical intervention on the large joints.
Author keywords:
Index keywords:
adult; article; blood; blood clotting; female; fibrinolysis; hemostasis; hip arthroplasty; human; male; middle aged; osteoarthritis; physiology; postoperative period; Adult; Arthroplasty, Replacement,
DOI:
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Смотреть в Scopus:
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84864384713&partnerID=40&md5=6427ed94724f5a4415024bca29b21132
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Link https://www.scopus.com/inward/record.uri?eid=2-s2.0-84864384713&partnerID=40&md5=6427ed94724f5a4415024bca29b21132
Correspondence Address Antropova, I.P.
PubMed ID 22645952
Language of Original Document Russian
Abbreviated Source Title Ross Fiziol Zh Im I M Sechenova
Source Scopus