Direct C-C coupling of phthalazine-N-oxide with the carboranyl anion - An original approach to C-modification of carboranes / Varaksin Mikhail V.,Galliamova Lidiia A.,Stepanova Olga A.,Eltsov Oleg S.,Chupakhin Oleg N.,Charushin Valery N. // JOURNAL OF ORGANOMETALLIC CHEMISTRY. - 2017. - V. 830, l. . - P. 93-99.

ISSN/EISSN:

0022-328X / 1872-8561

Type:

Article

Abstract:

An original transition metal-free approach based on the direct C-C coupling of phtalazine-N-oxide with the carboranyl anion has been developed. A series of the novel C-modified closo-carboranes such as 1-(2-oxido-3-acy1-3,4-dihydrophtalazinyl-4-yl)-1,2-dicarba-closo-dodecab oranes and 1-(2-formylbenzyl)-1,2-dicarba-closo-dodecaborane have been obtained. The synthesized boron clusters could be of interest as promising building blocks in design of BNCT delivery agents. (C) 2016 Elsevier B.V. All rights reserved.

Author keywords:

Carboranes; Phthalazine-N-oxide; C-C coupling NEUTRON-CAPTURE THERAPY; BIOLOGICAL EVALUATION; H FUNCTIONALIZATION; BACILLUS-ANTHRACIS; OPTICAL-PROPERTIES; BORON CLUSTERS; PHOSPHORESCENCE EFFICIENCY; IRIDIUM COMPLEXES; O-CARBORANES; DERIVATIVES

DOI:

10.1016/j.jorganchem.2016.11.0

Web of Science ID:

ISI:000394473200012

Соавторы в МНС:

Другие поля

Поле	Значение
Month	FEB 15
Publisher	ELSEVIER SCIENCE SA
Address	PO BOX 564, 1001 LAUSANNE, SWITZERLAND
Language	English
EISSN	1872-8561
Keywords-Plus	NEUTRON-CAPTURE THERAPY; BIOLOGICAL EVALUATION; H FUNCTIONALIZATION; BACILLUS-ANTHRACIS; OPTICAL-PROPERTIES; BORON CLUSTERS; PHOSPHORESCENCE EFFICIENCY; IRIDIUM COMPLEXES; O-CARBORANES; DERIVATIVES
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Inorganic \& Nuclear; Chemistry, Organic
Author-Email	chupakhin@ios.uran.ru
ResearcherID-Numbers	Varaksin, Mikhail/J-5007-2015
ORCID-Numbers	Varaksin, Mikhail/0000-0002-7997-3686
Funding-Acknowledgement	Ministry of Education and Science of the Russian Federation {[}4.6351.2017/BCh]; Russian Foundation for Basic Research {[}16-03-00958]
Funding-Text	The research was supported by the Ministry of Education and Science of the Russian Federation (Project No 4.6351.2017/BCh, synthesis of carboranes 4a-f) and the Russian Foundation for Basic Research (Project No 16-03-00958, synthesis of carborane 5).
Number-of-Cited-References	76
Usage-Count-Last-180-days	9
Usage-Count-Since-2013	9
Journal-ISO	J. Organomet. Chem.
Doc-Delivery-Number	EL2TN