The novel approaches towards fluoroalkyl-containing heteroannulated pyrimidines / Saloutin V. I.,Goryaeva M. V.,Khudina O. G.,Ivanova A. E.,Burgart Ya. V. // RUSSIAN CHEMICAL BULLETIN. - 2016. - V. 65, l. 7. - P. 1700-1708.

ISSN/EISSN:

1066-5285 / 1573-9171

Type:

Review

Abstract:

The review is focused on the synthesis of fluoroalkyl-containing heteroannulated pyrimidines via the reactions of alkyl 3-oxo-3-polyfluoroalkylpropionates and their ethoxymethylidene and 2-arylmethylidene derivatives with hetarylamines. Heteroannulation of polyfluoro-alkyl-containing pyrimidines is also discussed.

Author keywords:

heteroannulated pyrimidines; cyclization; alkyl 3-oxo-3-polyfluoroalkylpropionates; alkyl 3-oxo-3-polyfluoroalkyl-2-ethoxymethylidenepropionates; alkyl 2-arylmethylidene-3-oxo-3-polyfluoroalkylpropion PLASMODIUM-FALCIPARUM; DIHYDROOROTATE DEHYDROGENASE; MEDICINAL CHEMISTRY; DERIVATIVES; INHIBITORS; FLUORINE; ESTERS

DOI:

10.1007/s11172-016-1498-5

Web of Science ID:

ISI:000398191000004

Соавторы в МНС:

Другие поля

Поле	Значение
Month	JUL
Publisher	SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
EISSN	1573-9171
Keywords-Plus	PLASMODIUM-FALCIPARUM; DIHYDROOROTATE DEHYDROGENASE; MEDICINAL CHEMISTRY; DERIVATIVES; INHIBITORS; FLUORINE; ESTERS
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Author-Email	saloutin@ios.uran.ru
ResearcherID-Numbers	Burgart, Yanina/T-8025-2017
ORCID-Numbers	Burgart, Yanina/0000-0001-6061-2410
Funding-Acknowledgement	Ural Branch of the Russian Academy of Sciences {[}15-21-3-5]
Funding-Text	This work was financially supported by the Ural Branch of the Russian Academy of Sciences (Program No. 15-21-3-5).
Number-of-Cited-References	35
Usage-Count-Last-180-days	2
Usage-Count-Since-2013	2
Journal-ISO	Russ. Chem. Bull.
Doc-Delivery-Number	EQ6KU