Synthesis of new pyrrolo{[}2,1-a] phthalazine derivatives via multicomponent reaction of phthalazine with 1,1-dicyanoalkenes and alkyl isocyanides / Mironov Maxim A.,Shulepov Iliya D.,Kozhikhova Ksenia V.,Ivantsova Maria N.,Tokareva Maria I. // CHEMISTRY OF HETEROCYCLIC COMPOUNDS. - 2017. - V. 53, l. 4. - P. 430-433.

ISSN/EISSN:

0009-3122 / 1573-8353

Type:

Article

Abstract:

Multicomponent reactions between phthalazine, alkyl isocyanides, and 1,1-dicyanoalkenes in acetonitrile-water mixture produced high yields of substituted pyrrolo{[}2,1-a]phthalazines, which were converted upon treatment with 10\% hydrochloric acid to pyrrolo{[}2,1-a]-phthalazines unsubstituted at position 1. As a result, a range of new pyrrolo{[}2,1-a]phthalazine derivatives have been synthesized by this one-pot approach.

Author keywords:

isocyanides; phthalazine; decarboxylation; multicomponent reaction; one-pot synthesis FLUORESCENT PYRROLOPYRIDAZINE DERIVATIVES; CYCLOADDITIONS; WATER

DOI:

10.1007/s10593-017-2071-3

Web of Science ID:

ISI:000401912500007

Соавторы в МНС:

Другие поля

Поле	Значение
Month	APR
Publisher	SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
EISSN	1573-8353
Keywords-Plus	FLUORESCENT PYRROLOPYRIDAZINE DERIVATIVES; CYCLOADDITIONS; WATER
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
Author-Email	m.a.mironov@urfu.ru
ResearcherID-Numbers	Kozhikhova, Ksenia/I-8859-2017
ORCID-Numbers	Kozhikhova, Ksenia/0000-0001-5124-6826 , Maria/0000-0002-2389-0523
Number-of-Cited-References	21
Usage-Count-Last-180-days	3
Usage-Count-Since-2013	3
Journal-ISO	Chem. Heterocycl. Compds.
Doc-Delivery-Number	EV6VL