Synthesis of ortho-carboranyl derivatives of (S)-asparagine and (S)-glutamine / Gruzdev D. A.,Levit G. L.,Olshevskaya V. A.,Krasnov V. P. // RUSSIAN JOURNAL OF ORGANIC CHEMISTRY. - 2017. - V. 53, l. 5. - P. 769-776.

ISSN/EISSN:

1070-4280 / 1608-3393

Type:

Article

Abstract:

(S)-Asparagine and (S)-glutamine ortho-carboranyl derivatives with free amino and carboxy groups in the alpha-position were synthesized. By an example of N (gamma)-(1,2-dicarba-closo-dodecarboran-3-yl)-(S)-glutamine it was demonstrated that the developed synthetic approach carboranyl derivatives of amino acids allowed the preparation of optically pure isomers.

Author keywords:

GLUTAMIC-ACID DERIVATIVES; ALPHA-AMINO-ACIDS; PHARMACOPHORES; INHIBITORS; PEPTIDES; DELIVERY; ESTER; BORON

DOI:

10.1134/S1070428017050190

Web of Science ID:

ISI:000404735700019

Соавторы в МНС:

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Другие поля

Поле	Значение
Month	MAY
Publisher	MAIK NAUKA/INTERPERIODICA/SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013-1578 USA
Language	English
EISSN	1608-3393
Keywords-Plus	GLUTAMIC-ACID DERIVATIVES; ALPHA-AMINO-ACIDS; PHARMACOPHORES; INHIBITORS; PEPTIDES; DELIVERY; ESTER; BORON
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
Author-Email	gruzdev-da@ios.uran.ru
Funding-Acknowledgement	Russian Foundation for Basic Research {[}16-33-60122]
Funding-Text	The study was financially supported by the Russian Foundation for Basic Research (grant no. 16-33-60122).
Number-of-Cited-References	43
Usage-Count-Last-180-days	1
Usage-Count-Since-2013	1
Journal-ISO	Russ. J. Organ. Chem.
Doc-Delivery-Number	EZ5EO