Noncatalytic destruction of 5-acylcomanic acid esters in the presence of 2-methylindoles as a new method for the synthesis of indolylchalcones / Obydennov Dmitrii L.,Pan'kina Ekaterina O.,Sosnovskikh Vyacheslav Ya. // CHEMISTRY OF HETEROCYCLIC COMPOUNDS. - 2017. - V. 53, l. 8. - P. 924-926.

ISSN/EISSN:

0009-3122 / 1573-8353

Type:

Article

Abstract:

Ethyl esters of 5-acylcomanic acids reacted with 2-methylindoles in 3:1 propanol-water mixture in the absence of catalyst, resulting in pyrone ring opening and destruction of the molecular framework and leading to trans-indolylchalcones in 52-70\% yields.

Author keywords:

chalcones; indoles; 4-pyrones; alkenylation; ring destruction INDOLES; ALKENYLATION; DERIVATIVES; PYRROLES; FUNCTIONALIZATION; CHALCONES; POTENCY; 6-ARYL

DOI:

10.1007/s10593-017-2147-0

Web of Science ID:

ISI:000413601600018

Соавторы в МНС:

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Другие поля

Поле	Значение
Month	AUG
Publisher	SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
EISSN	1573-8353
Keywords-Plus	INDOLES; ALKENYLATION; DERIVATIVES; PYRROLES; FUNCTIONALIZATION; CHALCONES; POTENCY; 6-ARYL
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
Author-Email	dobydennov@mail.ru
Number-of-Cited-References	25
Journal-ISO	Chem. Heterocycl. Compds.
Doc-Delivery-Number	FK6GO