Polyfluoroalkylated 2-ethoxymethylene-3-oxo esters: synthesis and chemical properties overview / Saloutin Victor I.,Kudyakova Yulia S.,Goryaeva Marina V.,Burgart Yanina V.,Chupakhin Oleg N. // PURE AND APPLIED CHEMISTRY. - 2017. - V. 89, l. 8. - P. 1209-1222.

ISSN/EISSN:

0033-4545 / 1365-3075

Type:

Article; Proceedings Paper

Abstract:

The review focuses on the synthesis and chemical properties of polyfluoroalkylated 2-ethoxymethylene-3-oxo esters. The scope and peculiarities of their use as organic reagents in reactions with various N-, C-, O-, mono- and dinucleophiles are discussed in detail. The high reactivity of such derivatives is employed in the construction of enaminoketone, arene and heterocycle frameworks. Particular attention is paid to applications of these building blocks as chemicals for fine organic synthesis, bioactive compounds and metal complexes synthesis.

Author keywords:

2-ethoxymethylene-3-oxo esters; condensation; fluorinated building blocks; heterocycles; Mendeleev XX; open-chain ligands; tautomerization; transition metal complexes CARBOXAMIDE DERIVATIVES; NEMATOCIDAL ACTIVITY; MEDICINAL CHEMISTRY; ANTIFUNGAL ACTIVITY; ETHYL; FLUORINE; INHIBITOR; LIGANDS; COMPLEXES; DISCOVERY

DOI:

10.1515/pac-2016-1015

Web of Science ID:

ISI:000410090000016

Соавторы в МНС:

Другие поля

Поле	Значение
Month	AUG
Note	20th Mendeleev Congress on General and Applied Chemistry (Mendeleev), Ekaterinburg, RUSSIA, SEP 21-26, 2016
Organization	IUPAC
Publisher	WALTER DE GRUYTER GMBH
Address	GENTHINER STRASSE 13, D-10785 BERLIN, GERMANY
Language	English
EISSN	1365-3075
Keywords-Plus	CARBOXAMIDE DERIVATIVES; NEMATOCIDAL ACTIVITY; MEDICINAL CHEMISTRY; ANTIFUNGAL ACTIVITY; ETHYL; FLUORINE; INHIBITOR; LIGANDS; COMPLEXES; DISCOVERY
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Author-Email	victor.saloutin@yandex.ru
ResearcherID-Numbers	Burgart, Yanina/T-8025-2017
ORCID-Numbers	Burgart, Yanina/0000-0001-6061-2410
Funding-Acknowledgement	Russian Foundation for Basic Research {[}16-33-60048 mol\_a\_dk]; Leading Scientific Schools of the Russian Federation {[}NSh-8922.2016.3]
Funding-Text	The authors gratefully acknowledge Russian Foundation for Basic Research (grant no. 16-33-60048 mol\_a\_dk) and the State Program for Supporting of Leading Scientific Schools of the Russian Federation (grant no. NSh-8922.2016.3) for financial support.
Number-of-Cited-References	75
Usage-Count-Last-180-days	2
Usage-Count-Since-2013	2
Journal-ISO	Pure Appl. Chem.
Doc-Delivery-Number	FG3QD