Synthesis, crystal structure and biological activity of N′-tert-butyl-N-(3-methoxylbenzoyl)-N-(4-methyl-1,2, 3-thiadiazole-5- formylhydrazine / Huang J., Wang H., Fan Z.-J., Song H.-B., Zhao H., Huang Y., Prokhorova P.E., Belskaya N.P., Morzherin Y.Yu., Bakulev V.A. // Journal of Chemical Crystallography. - 2011. - V. 41, l. 12. - P. 1860-1865.

ISSN:

10741542

Type:

Article

Abstract:

The title compound, N'-tert-butyl-N-(3-methoxylbenzoyl)- N-(4-methyl-1,2,3-thiadiazole-5-formylhydrazine (C 16H 20N 4O 3S) was prepared from the reaction of 4-methyl-1, 2,3-thiadiazole-5-carbonyl chloride with N'-tert-Butyl-3- methoxylbenzohydrazine, and its structure was characterized by 1Hydrogen Nuclear Magnetic Resonance, High-Resolution Mass Spectrometry, IR spectra, and single crystal X-ray diffraction. The crystal of the title compound belongs to monoclinic system, space group P 21/c with cell parameters a = 17.986(2) Å, b = 8.0180(10) Å, c = 12.0190(14) Å, α = 90°, β = 91.160(5)°, γ = 90°, V = 1732.9(4) Å 3, Z = 4, D c = 1.335 g/cm 3, l (Mo Ka) = 0.209 mm -1, F (000) = 736, R = 0.0367 and wR = 0.0932. X-ray diffraction analysis indicates that all rings in the title compound are non-planar. The bioassay results indicated that, the title compound had good fungicide activity against Sclerotinia sclerotiorum, certain extent of insecticidal activity against Plutella xylostella L. © Springer Science+Business Media, LLC 2011.

Author keywords:

Biological activity; Diacylhydrazine; Single crystal structure; Synthesis; X-ray diffraction

Index keywords:

Plutella xylostella; Sclerotinia sclerotiorum

DOI:

10.1007/s10870-011-0189-1

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https://www.scopus.com/inward/record.uri?eid=2-s2.0-84855836255&doi=10.1007%2fs10870-011-0189-1&partnerID=40&md5=6358f00b439481af69392913c85a1e72

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Link	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84855836255&doi=10.1007%2fs10870-011-0189-1&partnerID=40&md5=6358f00b439481af69392913c85a1e72
Affiliations	Department of Plant Pathology, Sichuan Agricultural University, No. 555 Northeast Road, Wenjiang District, Chengdu 611130, Sichuan, China; State Key Laboratory of Elemento Organic Chemistry, Nankai University, 94 Weijin Road, Nankai District, Tianjin 300071, China; Ural Federal University Named, Ekaterinburg, 620002, Russian Federation
Author Keywords	Biological activity; Diacylhydrazine; Single crystal structure; Synthesis; X-ray diffraction
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Correspondence Address	Fan, Z.-J.; State Key Laboratory of Elemento Organic Chemistry, Nankai University, 94 Weijin Road, Nankai District, Tianjin 300071, China; email: fanzj@nankai.edu.cn
Language of Original Document	English
Abbreviated Source Title	J. Chem. Crystallogr.
Source	Scopus