Reactions of 5-dialkylamino-1,2,3-thiadiazole-4-carbaldehydes with amines as a method for the synthesis of 1,2,3-triazole-4-carbothioamides / Glukhareva T.V., Morzherin Yu.Yu., Dyudya L.V., Malysheva K.V., Tkachev A.V., Padva A., Bakulev V.A. // Russian Chemical Bulletin. - 2004. - V. 53, l. 6. - P. 1311-1317.

ISSN:

10665285

Type:

Article

Abstract:

A method for the synthesis of previously inaccessible 5-dialkylamino- substituted 1,2,3-thiadiazole-4-carbaldehydes was developed. Ring transformation in these compounds induced by primary aliphatic and aromatic amines, hydroxylamines, and N-substituted hydrazines resulted in the synthesis of a broad range of 1,2,3-triazole-4-carbothioamide.

Author keywords:

1,2,3-thiadiazole; 1,2,3-triazole; Cornfort rearrangement; nucleophilic substitution; oxidation; reduction; thioamides

Index keywords:

aldehyde derivative; amine; thioamide; triazole derivative; article; chemical reaction kinetics; drug synthesis; substitution reaction

DOI:

10.1023/B:RUCB.0000042292.1911

Смотреть в Scopus:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-4644245422&doi=10.1023%2fB%3aRUCB.0000042292.19119.3d&partnerID=40&md5=110c361bca84a785525040bb80040c42

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Link	https://www.scopus.com/inward/record.uri?eid=2-s2.0-4644245422&doi=10.1023%2fB%3aRUCB.0000042292.19119.3d&partnerID=40&md5=110c361bca84a785525040bb80040c42
Affiliations	Urals State Technical University, 19 Ul. Mira, 620002 Ekaterinburg, Russ. Fed., Russian Federation; N. N. Vorozhtsov Novosibirsk I., Siberian Br. Russ. Acad. of Sci., 9 Prosp. Akad. Lavrenteva, 630090 N., Russian Federation; Emory University, Department of Chemistry, 1515, Pierce Dr., Atlanta G., United States
Author Keywords	1,2,3-thiadiazole; 1,2,3-triazole; Cornfort rearrangement; nucleophilic substitution; oxidation; reduction; thioamides
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Correspondence Address	Urals State Technical University, 19 Ul. Mira, 620002 Ekaterinburg, Russ. Fed.Russian Federation; email: morjerine@htf.ustu.ru
Language of Original Document	English
Abbreviated Source Title	Russ. Chem. Bull.
Source	Scopus