Synthesis of novel thiazolidin-4-ones by reaction of malonthioamide derivatives with dimethyl acetylenedicarboxylate / Berseneva V.S., Tkachev A.V., Morzherin Y.Yu., Dehaen W., Luyten I., Toppet S., Bakulev V.A. // Journal of the Chemical Society - Perkin Transactions 1. - 1998. - V. , l. 14. - P. 2133-2136.

ISSN:
0300922X
Type:
Article
Abstract:
Novel 2,5-dimethylenethiazolidin-4-one derivatives have been prepared by reaction of malonthioamide derivatives with dimethyl acetylenedicarboxylate. These compounds exist as separate (E,Z)- and (Z,Z)-isomers or as a mixture. The (E,Z)-isomer is formed as the initial product which transforms to the (Z,Z)-isomer under mild conditions. The structures of the obtained compounds have been confirmed by IR and NMR spectroscopy.
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Affiliations Department of Technology and Organic Synthesis, Ural State Technical University, 620002, Ekaterinburg, Russian Federation; Novosibirsk's Institute of Organic Chemistry, 630090, Novosibirsk, Russian Federation; Department of Chemistry, University of Leuven, Celestijnenlaan 200F, 3001 Leuven (Heverlee), Belgium
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Correspondence Address Dehaen, W.; Department of Chemistry, University of Leuven, Celestijnenlaan 200F, 3001 Leuven (Heverlee), Belgium
Language of Original Document English
Source Scopus