Non-natural nucleosides based on 1,2,4-triazolo[1,5-a]pyrimidin-7-ones / Chupakhin O.N., Shestakova T.S., Deev S.L., Eltsov O.S., Rusinov V.L. // Heterocycles. - 2010. - V. 80, l. 2. - P. 1149-1163.

ISSN:
03855414
Type:
Article
Abstract:
Two methods for synthesis of new nucleosides bearing 6-phenyl-l,2,4- triazolo[l,5-a]pyrimidin-7-ones as a base have been developed. The first one includes Vorbrggen glycosylation reaction. The second method, which is effective for synthesis of acyclic nucleosides, is based on the condensation between sodium salts of 6-phenyl-1,2,4-triazolo [1,5-a]pyrimidin-7-ones and 4-bromobuthyl acetate or (Z)-4-bromobut-2-en-1-yl acetate. © 2010 The Japan Institute of Heterocyclic Chemistry Received.
Author keywords:
1,2,4-Triazolo[1,5-a]pyrimidin-7- one; Alkyl Fragment; Glycosylation; Non-Natural Nucleoside; Nucleoside Analog
Index keywords:
нет данных
DOI:
10.3987/COM-09-S(S)97
Смотреть в Scopus:
https://www.scopus.com/inward/record.uri?eid=2-s2.0-77955667692&doi=10.3987%2fCOM-09-S%28S%2997&partnerID=40&md5=f35fa2c8860e253f97d516760160defe
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Link https://www.scopus.com/inward/record.uri?eid=2-s2.0-77955667692&doi=10.3987%2fCOM-09-S%28S%2997&partnerID=40&md5=f35fa2c8860e253f97d516760160defe
Affiliations Department of Organic Chemistry, Ural State Technical University, 19 Mira St., Ekaterinburg 620002, Russian Federation; Institute of Organic Synthesis, Russian Academy of Sciences, 22 S. St., Ekaterinburg 620002, Russian Federation
Author Keywords 1,2,4-Triazolo[1,5-a]pyrimidin-7- one; Alkyl Fragment; Glycosylation; Non-Natural Nucleoside; Nucleoside Analog
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Correspondence Address Chupakhin, O. N.; Department of Organic Chemistry, Ural State Technical University, 19 Mira St., Ekaterinburg 620002, Russian Federation; email: chupakhin@ios.uran.ru
CODEN HTCYA
Language of Original Document English
Abbreviated Source Title Heterocycles
Source Scopus