Synthesis and transformations of (imidazolylimino)thiazolidinones / El'tsov O.S., Mokrushin V.S., Bel'skaya N.P., Kozlova N.M. // Russian Chemical Bulletin. - 2003. - V. 52, l. 2. - P. 461-466.

ISSN:

10665285

Type:

Article

Abstract:

The reaction of ethyl 5-phenylthioureido-3H-imidazole-4-carboxylate with bromoacetic acid afforded (imidazolylimino)thiazolidinones, which were transformed into the corresponding 5-arylidene-4-thiazolidinones by the reactions with aldehydes. Under the conditions of the Knoevenagel reaction, the thiazolidine ring in derivatives of 4-(4-oxothiazolidin-2-ylidene-amino)-3H- imidazole-4-carboxamides was opened to form substituted guanidines.

Author keywords:

α-haloalkanoic acids and their esters; (imidazolylimino)thiazolidinone; 5-arylidene-4- thiazolidinones; Aldehydes; Guanidines; Imidazolylisothiourea; Imidazolylthiourea

Index keywords:

aldehyde; amide; bromoacetic acid; carboxylic acid derivative; ethyl 5 phenylthioureido 3h imidazole 4 carboxylate; guanidine derivative; thiazolidine derivative; unclassified drug; article; chemical

DOI:

10.1023/A:1023439706631

Смотреть в Scopus:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-1642565354&doi=10.1023%2fA%3a1023439706631&partnerID=40&md5=2398394524901517614cbc4b9a9c7eda

Соавторы в МНС:

Другие поля

Поле	Значение
Link	https://www.scopus.com/inward/record.uri?eid=2-s2.0-1642565354&doi=10.1023%2fA%3a1023439706631&partnerID=40&md5=2398394524901517614cbc4b9a9c7eda
Affiliations	Urals State Technical University, 19 ul. Mira, 620002 Ekaterinburg, Russian Federation
Author Keywords	α-haloalkanoic acids and their esters; (imidazolylimino)thiazolidinone; 5-arylidene-4- thiazolidinones; Aldehydes; Guanidines; Imidazolylisothiourea; Imidazolylthiourea
Chemicals/CAS	amide, 17655-31-1; bromoacetic acid, 68-10-0, 79-08-3
References	Eltsov, O.S., Mokrushin, V.S., Rybalova, T.V., Gatilov, Y.V., Tkachev, A.V., (2000) Mendeleev Commun., p. 233; El'tsov, O.S., Mokrushin, V.S., (2002) Izv. Akad. Nauk, Ser. Khim., p. 506; (2002) Russ. Chem. Bull., Int. Ed., 51, p. 547; Griffin, T.S., Woods, T.S., Klayman, D.L., (1975) Adv. Heterocycl. Chem., 18, p. 99; Hesse, M., Meier, H., Zeeh, B., (1997) Spectroscopic Methods in Organic Chemistry, 365p. , Thieme, New York; Mishra, S., Srivastava, S.K., Srivastava, S.D., (1997) Ind. J. Chem., Sect. B: Org. Chem. Incl. Med. Chem., 36 B, p. 826; Feichtinger, K., Zapf, C., Sings, H.L., Goodman, M., (1998) J. Org. Chem., 63, p. 3804; Cook, A.H., Davis, A.C., Heilbron, I., Thomas, G.H., (1949) J. Chem. Soc., p. 1071; Wang, Y., Lowe, P.R., Thomson, W.T., Clark, J., Stevens, M.F.G., (1997) Chem. Commun., p. 363
Correspondence Address	El'tsov, O.S.; Urals State Technical University, 19 ul. Mira, 620002 Ekaterinburg, Russian Federation; email: eltsov@htf.ustu.ru
Language of Original Document	English
Abbreviated Source Title	Russ. Chem. Bull.
Source	Scopus