Reactions of 2-(trifluoromethyl)chromones with cyanoacetamides, ethyl cyanoacetate and diethyl malonate. Unexpected synthesis of benzo[c]coumarin derivatives / Sosnovskikh V.Y., Safrygin A.V., Anufriev V.A., Eltsov O.S., Iaroshenko V.O. // Tetrahedron Letters. - 2011. - V. 52, l. 47. - P. 6271-6274.

ISSN:
00404039
Type:
Article
Abstract:
While 2-(trifluoromethyl)chromones react with cyanoacetamides in the presence of sodium ethoxide to produce 6-(2-hydroxyaryl)-4-(trifluoromethyl)-2- oxo-1,2-dihydropyridine-3-carbonitriles, their reactions with ethyl cyanoacetate and diethyl malonate under the same conditions took an entirely different course and gave novel functionalized derivatives of 6H-benzo[c]chromen-6-one. © 2011 Elsevier Ltd. All rights reserved.
Author keywords:
2-Pyridones; 6H-Benzo[c]chromen-6-one; Active methylene compounds; Chromones; Trifluoromethylated heterocycles
Index keywords:
2 (trifluoromethyl)chromone derivative; chromone derivative; coumarin derivative; cyanoacetamide derivative; ethyl cyanoacetate; malonic acid diethyl ester; unclassified drug; article; polymerization;
DOI:
10.1016/j.tetlet.2011.09.082
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https://www.scopus.com/inward/record.uri?eid=2-s2.0-80054871470&doi=10.1016%2fj.tetlet.2011.09.082&partnerID=40&md5=4a2a3b3bd862761d6c4bce200bb935d4
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Link https://www.scopus.com/inward/record.uri?eid=2-s2.0-80054871470&doi=10.1016%2fj.tetlet.2011.09.082&partnerID=40&md5=4a2a3b3bd862761d6c4bce200bb935d4
Affiliations Department of Chemistry, Ural State University, pr. Lenina 51, 620083 Ekaterinburg, Russian Federation; Department of Chemistry, Ural Federal University, St. Mira 19, 620002 Ekaterinburg, Russian Federation; Institut für Chemie, Universität Rostock, Albert-Einstein-Strasse 3a, 18059 Rostock, Germany
Author Keywords 2-Pyridones; 6H-Benzo[c]chromen-6-one; Active methylene compounds; Chromones; Trifluoromethylated heterocycles
Chemicals/CAS malonic acid diethyl ester, 105-53-3
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Correspondence Address Sosnovskikh, V.Y.; Department of Chemistry, Ural State University, pr. Lenina 51, 620083 Ekaterinburg, Russian Federation; email: sosn1951@mail.ru
CODEN TELEA
Language of Original Document English
Abbreviated Source Title Tetrahedron Lett.
Source Scopus