Evaluation of the Debye temperature for iron cores in human liver ferritin and its pharmaceutical analogue, Ferrum Lek, using Mössbauer spectroscopy / Dubiel S.M., Cieślak J., Alenkina I.V., Oshtrakh M.I., Semionkin V.A. // Journal of Inorganic Biochemistry. - 2014. - V. 140, l. . - P. 89-93.

ISSN:
01620134
Type:
Article
Abstract:
An iron-polymaltose complex, Ferrum Lek, used as antianemic drug and considered as a ferritin analogue and human liver ferritin were investigated in the temperature range of 295-90 K using 57Fe Mössbauer spectroscopy with a high velocity resolution (in 4096 channels). This study aimed to make a comparison of the Fe atom dynamics in the Ferrum Lek and ferritin iron cores by means of evaluation of the Debye temperature using the temperature dependence of the spectral center shift obtained with two different fitting procedures and the second order Doppler shift approach. The Debye temperature, evaluated as ΘD = 502 ± 24 K for Ferrum Lek and ΘD = 461 ± 16 K for human liver ferritin, demonstrated a very small difference in the Fe atom vibrations, reflecting a slightly smaller rigidity in the iron cores in human liver ferritin. © 2014 Elsevier Inc.
Author keywords:
Debye temperature; Ferrum Lek; Human liver ferritin; Iron core
Index keywords:
ferritin; iron saccharate; ferritin; iron; ferritin; iron saccharate; accuracy; anisotropy; article; atom; controlled study; debye temperature; dynamics; evaluation study; human; human tissue; isomer;
DOI:
10.1016/j.jinorgbio.2014.07.00
Смотреть в Scopus:
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84905190914&doi=10.1016%2fj.jinorgbio.2014.07.005&partnerID=40&md5=e5caace8a6895cb770d60811cfd35687
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Link https://www.scopus.com/inward/record.uri?eid=2-s2.0-84905190914&doi=10.1016%2fj.jinorgbio.2014.07.005&partnerID=40&md5=e5caace8a6895cb770d60811cfd35687
Affiliations AGH University of Science and Technology, Faculty of Physics and Applied Computer Science, PL-30-059 Kraków, Poland; Department of Physical Techniques and Devices for Quality Control, Institute of Physics AndTechnology, Ural Federal University, Ekaterinburg 620002, Russian Federation; Department of Experimental Physics, Institute of Physics and Technology, Ural Federal University, Ekaterinburg 620002, Russian Federation
Author Keywords Debye temperature; Ferrum Lek; Human liver ferritin; Iron core
Chemicals/CAS ferritin, 9007-73-2; iron saccharate, 63530-05-2, 8047-67-4; iron, 14093-02-8, 53858-86-9, 7439-89-6; Ferritins; Iron
Tradenames ferrum lek
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Correspondence Address Dubiel, S.M.; AGH University of Science and Technology, Faculty of Physics and Applied Computer Science, PL-30-059 Kraków, Poland; email: Stanislaw.Dubiel@fis.agh.edu.pl
Publisher Elsevier Inc.
CODEN JIBID
PubMed ID 25086236
Language of Original Document English
Abbreviated Source Title J. Inorg. Biochem.
Source Scopus