Study of the relationship of small variations of the molecular structure and the iron state in iron containing proteins by Mössbauer spectroscopy: Biomedical approach / Oshtrakh M.I. // Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy. - 2004. - V. 60, l. 1-2. - P. 217-234.

ISSN:
13861425
Type:
Review
Abstract:
This review considers the results of experimental Mössbauer studies and theoretical calculations of the effect of small variations of protein molecular structure on the iron electronic structure and stereochemistry in order to understand the proteins structural heterogeneity and functional variety. Structural changes in iron containing proteins during various diseases are also considered. These results show the relationship of the small structural variations and Mössbauer parameters of iron containing proteins and demonstrate the possibilities of Mössbauer spectroscopy to obtain new information at the molecular level in biomedical research. © 2003 Elsevier B.V. All rights reserved.
Author keywords:
Biomedical research; Ferritin; Hemoglobin; Iron electronic structure and stereochemistry; Mössbauer spectroscopy
Index keywords:
Biomedical engineering; Disease control; Electronic structure; Iron compounds; Molecular structure; Molecular vibrations; Mossbauer spectroscopy; Pathology; Stereochemistry; Biomolecules; Spin states;
DOI:
10.1016/S1386-1425(03)00209-9
Смотреть в Scopus:
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0348208968&doi=10.1016%2fS1386-1425%2803%2900209-9&partnerID=40&md5=5bbe8094d77cb9572daa80b6340b298f
Соавторы в МНС:
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Link https://www.scopus.com/inward/record.uri?eid=2-s2.0-0348208968&doi=10.1016%2fS1386-1425%2803%2900209-9&partnerID=40&md5=5bbe8094d77cb9572daa80b6340b298f
Affiliations Division of Applied Biophysics, Fac. Phys. Tech./Devices Qual. Ctrl., Ural State Technical University, Ekaterinburg 620002, Russian Federation
Author Keywords Biomedical research; Ferritin; Hemoglobin; Iron electronic structure and stereochemistry; Mössbauer spectroscopy
Chemicals/CAS ferritin, 9007-73-2; heme, 14875-96-8; hemoglobin, 9008-02-0; iron, 14093-02-8, 53858-86-9, 7439-89-6; Ferritins, 9007-73-2; Heme, 14875-96-8; Hemoglobins; Iron, 7439-89-6
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Correspondence Address Oshtrakh, M.I.; Division of Applied Biophysics, Fac. Phys. Tech./Devices Qual. Ctrl., Ural State Technical University, Ekaterinburg 620002, Russian Federation; email: oshtrakh@mail.utnet.ru
CODEN SAMCA
PubMed ID 14670481
Language of Original Document English
Abbreviated Source Title Spectrochim. Acta Part A Mol. Biomol. Spectrosc.
Source Scopus