State of synapses of the cortex of cerebral hemispheres on γ-irradiation / Gaidamakin N.A., Ushakov I.B. // Neuroscience and Behavioral Physiology. - 1989. - V. 19, l. 6. - P. 483-488.

ISSN:

00970549

Type:

Article

Abstract:

In adult rats with developing neurological disorders we detected destructive changes in most of the synapses of the brain sensorimotor cortex 1.6-4.3 h after a single dose of γ-irradiation (200 Gy). All functionally important parts on the axonal and dendritic sides of the synapses had undergone changes: mitochondria, synaptic vesicles, pre- and postsynaptic membranes, synaptic complexes, and subsynaptic consolidations, axonal and dendritic plasma, and their inclusions. These changes possibly cause disconnection of the neurons and provide a structural basis for neurological deficiencies following a high substantial ionizing radiation. © 1989 Plenum Publishing Corporation.

Author keywords:

Index keywords:

animal; article; brain cortex; male; pathology; radiation exposure; radiation injury; rat; synapse; ultrastructure; Animal; Cerebral Cortex; Male; Radiation Injuries, Experimental; Rats; Synapses

DOI:

10.1007/BF01181863

Смотреть в Scopus:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0024760856&doi=10.1007%2fBF01181863&partnerID=40&md5=f0578cd4b868109e49320dded8f1764f

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References	Baisogolov, G.D., (1978) Med. Radiol., 23 (7), pp. 62-68; N. N. Bogolepov, Ultrastructure of Synapses under Normal and Pathological Conditions [in Russian], Moscow (1975); N. A. Gaidamakin, Efficient Method for Fixation of Biological Objects Using a Chrome-Osmium Mixture for Electron Microscopy [in Russian], Pushchino (1980); Dedov, I.I., Voitkevich, A.A., (1970) Tsitologiya, 12 (2), pp. 243-245; N. S. Kositsyn, Microstructure of Dendrites and Axodendritic Connections in the Central Nervous System [in Russian], Moscow (1976); S. Kuffler and J. Nichols, From the Neuron to the Brain [Russian translation], Moscow (1979); A. Lehninger, Biochemistry. Molecular Basis of the Structure and Function of Cells [Russian translation], Moscow (1976); A. G. Panov and I. I. Ulitovskaya, Current Aspects of Neuropathology [in Russian], Kursk (1970), pp. 177–180; Romantsev, E.F., Pushkareva, N.B., Kuznetsova, E.V., (1979) Radiobiologiya, 19 (4), pp. 525-531; D. A. Sakharov, General Physiology of the Nervous System [in Russian], Leningrad (1979), pp. 218–277; B. Weekly, Electron Microscopy for Beginners [Russian translation], Moscow (1975); Ushakov, I.E., Fedorov, V.P., (1983) Radiobiologiya, 23 (3), pp. 372-375; Ushakov, I.B., Fedorov, V.P., (1983) Radiobiologiya, 23 (3), pp. 372-375; Hackenbrock, C.R., (1968) J. Cell Biol., 37, pp. 345-369; Uchizono, K., (1965) Nature, 207, pp. 642-643
Publisher	Kluwer Academic Publishers
CODEN	NBHPB
PubMed ID	2615962
Language of Original Document	English
Abbreviated Source Title	Neurosci Behav Physiol
Source	Scopus