New catalytic system for the synthesis of imidazo[1,2-a]pyridines by the Ugi reaction / Mironov M.A., Tokareva M.I., Ivantsova M.N., Mokrushin V.S. // Russian Chemical Bulletin. - 2006. - V. 55, l. 10. - P. 1835-1839.

ISSN:

10665285

Type:

Article

Abstract:

A combination of N-hydroxysuccinimide and p-toluenesulfonic acid is proposed as an efficient catalyst for the preparation of a great variety of imidazo[1,2-a]pyridine derivatives by three-component condensation of aromatic isocyanides, aldehydes, and 2-aminopyridine. The advantages of this procedure are high yields of the target products and the absence of side reactions. © 2006 Springer Science+Business Media, Inc.

Author keywords:

Catalysis; Combinatorial synthesis; Imidazo[1,2-a]pyridine; Isocyanides; Ugi reaction

Index keywords:

нет данных

DOI:

10.1007/s11172-006-0494-6

Смотреть в Scopus:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-33947103093&doi=10.1007%2fs11172-006-0494-6&partnerID=40&md5=20879fc07959bdd53e0e63c6dba0513d

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Поле	Значение
Link	https://www.scopus.com/inward/record.uri?eid=2-s2.0-33947103093&doi=10.1007%2fs11172-006-0494-6&partnerID=40&md5=20879fc07959bdd53e0e63c6dba0513d
Affiliations	Ural State Technical University, 19 ul. Mira, 620002 Ekaterinburg, Russian Federation
Author Keywords	Catalysis; Combinatorial synthesis; Imidazo[1,2-a]pyridine; Isocyanides; Ugi reaction
References	Sabalayrolles, C., Gros, G.H., Milhavet, J.C., Rechenq, E., Chapat, J.P., Boucard, M., McNeill, J.H., (1984) J. Med. Chem, 27, p. 206; Kaminski, J.J., Wallmark, B., Briving, C., Andersson, B.M., (1991) J. Med. Chem, 34, p. 533; Rival, Y., Grassy, G., Michel, G., (1992) Chem. Pharm. Bull, 40, p. 1170; Fisher, M.H., Lusi, A., (1972) J. Med. Chem, 15, p. 982; Gröbke, K., Weber, L., Mehlin, F., (1998) Synlett, p. 661; Bienayme, H., Bouzid, K., (1998) Angew. Chem., Int. Ed, 37, p. 2234; Blackburn, C., Guan, B., Fleming, P., Shiosaki, K., Tsai, S., (1998) Tetrahedron Lett, 39, p. 3635; Dömling, A., (2006) Chem. Rev, 106, p. 17; Weber, L., Illgen, K., Almstetter, M., (1999) Synlett, p. 366; Chen, J.J., Golebiowski, A., Klopfenstein, S.R., McClenaghan, J., Peng, S.X., Portlock, D.E., West, L., (2001) Synlett, p. 1260; Henkel, B., Weber, L., (2002) Synlett, p. 1877; El Kaïm, L., Grimaud, L., Oble, J., (2005) Angew. Chem., Int. Ed, 44, p. 7961; Mironov, M.A., Ivantsova, M.N., Tokareva, M.I., Mokrushin, V.S., (2005) Tetrahedron Lett, 46, p. 3957; Mironov, M.A., Ivantsova, M.N., Mokrushin, V.S., (2006) Synlett, p. 615
Correspondence Address	Mironov, M.A.; Ural State Technical University, 19 ul. Mira, 620002 Ekaterinburg, Russian Federation; email: mirma@htf.ustu.ru
Language of Original Document	English
Abbreviated Source Title	Russ. Chem. Bull.
Source	Scopus