Interaction of 3,8-disubstituted imidazo-[5,1-C][1,2,4]triazines with nucleophiles / Sadchikova E.V., Mokrushin V.S. // Chemistry of Heterocyclic Compounds. - 2014. - V. 50, l. 7. - P. 1014-1020.

ISSN:

00093122

Type:

Article

Abstract:

We studied the reactivity of diethyl 4-aminoimidazo[5,1-c][1,2,4]triazine-3,8-dicarboxylate in reactions with nucleophiles and demonstrated the possibility of selective formation of monoamides by interaction with primary and secondary aliphatic amines. It was determined that the carbon atom at position 4 of imidazo[1,5-c][1,2,4]triazine system underwent nucleophilic attack, enabling the synthesis of imidazo-[1',5':3,4][1,2,4]triazino[5,6-b][1,5]benzoxazepines and imidazo[1',5':3,4][1,2,4]triazino[5,6-b][1,5]benzo- diazepines, as well as (pyrazol-4-ylidenehydrazino)imidazoles, depending on the bisnucleophile used. © 2014 Springer Science+Business Media New York.

Author keywords:

diazepines; imidazolylhydrazones; imidazotriazines; oxazepines; polycondensed heterocyclic systems

Index keywords:

нет данных

DOI:

10.1007/s10593-014-1557-5

Смотреть в Scopus:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84919906875&doi=10.1007%2fs10593-014-1557-5&partnerID=40&md5=31cbff1ce8c55083652bde79f273c119

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Поле	Значение
Link	https://www.scopus.com/inward/record.uri?eid=2-s2.0-84919906875&doi=10.1007%2fs10593-014-1557-5&partnerID=40&md5=31cbff1ce8c55083652bde79f273c119
Affiliations	Ural Federal University Named after the First President of Russia B. N. Yeltsin, 19 Mira St., Yekaterinburg, Russian Federation
Author Keywords	diazepines; imidazolylhydrazones; imidazotriazines; oxazepines; polycondensed heterocyclic systems
Funding Details	14-03-01033, RFBR, Russian Foundation for Basic Research
References	Bezmaternykh, M.A., Mokrushin, V.S., Pospelova, T.A., El'Tsov, O.S., (1998) Khim. Geterotsikl. Soedin., 805. , [Chem. Heterocycl. Compd., 34, 702 (1998); Mokrushin, V.S., Sadchikova, E.V., (2013) Chemistry of Heterocyclic Diazo Compounds [In Russian], , Prospekt Nauki St. Petersburg; Mokrushin, V.S., Ofitserov, B.I., Rapakova, T.V., Tsaur, A.G., Pushkareva, Z.V., (1976) Khim. Geterotsikl. Soedin., 556. , [Chem. Heterocycl. Compd., 12, 465 (1976); Nifontov, V.I., Selezneva, I.S., Mokrushin, V.S., Pushkareva, Z.V., Trofimov, V.A., (1979) Khim. Geterotsikl. Soedin., 984. , [Chem. Heterocycl. Compd., 15, 805 (1979); Sadchikova, E.V., Mokrushin, V.S., (2003) Izv. Akad. Nauk, Ser. Khim., 7, p. 1516. , [Russ. Chem. Bull., 52, 1600 (2003); Shealy, Y.F., Krauth, C.A., Pittillo, R., Hunt, D.E., (1967) J. Pharm. Sci., 56, p. 147. , 1:CAS:528:DyaF2sXlsVWgtg%3D%3D
Correspondence Address	Sadchikova, E.V.; Ural Federal University Named after the First President of Russia B. N. Yeltsin, 19 Mira St., Russian Federation
Publisher	Springer New York LLC
CODEN	CHCCA
Language of Original Document	English
Abbreviated Source Title	Chem. Heterocycl. Compd.
Source	Scopus