Mechanisms of changes in the hemoglobin profile during acute adaptation to extreme conditions / Chereshnev V.A., Sumin M.N., Rezaikin A.V., Yushkov B.G. // Bulletin of Experimental Biology and Medicine. - 2002. - V. 134, l. 3. - P. 223-225.

ISSN:

00074888

Type:

Article

Abstract:

We studied changes in rat hemoglobin isoforms during acute adaptation to various hypoxic conditions. Erythrocytes were heterogeneous in the content of various hemoglobin isoforms. Changes in the hemoglobin profile during hypoxia are related to variations in the ratio between populations of erythrocytes differing in the content of individual hemoglobin isoforms.

Author keywords:

Adaptation; Erythrocyte heterogeneity; Hemoglobin isoforms

Index keywords:

hemoglobin; adaptation; animal cell; animal experiment; animal model; article; bleeding; bone marrow; cell heterogeneity; cell membrane; cell population; controlled study; erythrocyte; hematopoietic s

DOI:

10.1023/A:1021434929785

Смотреть в Scopus:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036770714&doi=10.1023%2fA%3a1021434929785&partnerID=40&md5=fc3a5026763756c8320e00fc7bff352f

Соавторы в МНС:

Другие поля

Поле	Значение
Link	https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036770714&doi=10.1023%2fA%3a1021434929785&partnerID=40&md5=fc3a5026763756c8320e00fc7bff352f
Affiliations	Ekaterinburg Br. Inst. Ecol./Genet., Ural Division, Russian Academy of Sciences, Ural, Russian Federation
Author Keywords	Adaptation; Erythrocyte heterogeneity; Hemoglobin isoforms
Chemicals/CAS	hemoglobin, 9008-02-0; Hemoglobins; Protein Isoforms
References	Borisyuk, M.V., (1983) Usp. Fiziol. Nauk, 14 (1), pp. 85-101; (2000) Hypoxia. Adaptation, Pathogenesis, and Clinics, , [in Russian], St. Petersburg; Maurer, G., (1971) Disk Electrophoresis. Theory and Practice of Electrophoresis in Polyacrylamide Gel, , [in Russian], Moscow; Pavlov, A.D., Morshchakova, E.F., (1987) Regulation of Erythropoiesis, , [in Russian], Moscow; Starodub, N.F., Nazarenko, V.I., (1987) Heterogeneous System of Hemoglobin. Structure, Properties, Synthesis, and Biological Role, , [in Russian], Kiev; Starodub, N.F., Artyukhov, V.P., Gritsak, A.N., Radavskii, Y.L., (1979) Ukr. Biokhim. Zh., 51 (2), pp. 117-129; Bard, H., Fourton, J.C., Gagnon, C., Gagnon, G., (1994) J. Pediatr., 124 (6), pp. 941-943; Barker, J.E., (1980) Blood, 56, pp. 495-500; Barker, J.E., Pierce, J.E., Nienhuis, A.W., (1979) Cellular and Molecular Regulation of Hemoglobin Switching, pp. 179-192. , Eds. G. Stamatoyannopoulos and A. W. Nienhuis, New York; Kleihauer, E., Tang, T.E., Petke, K., (1967) Acta Haematol., 38, pp. 264-272; Umemura, T., Al-Khatti, A., Papayannopoulou, T., Stamatoyannopoulosu, G., (1988) Proc. Natl. Acad. Sci. USA, 23, pp. 9278-9282
PubMed ID	12511986
Language of Original Document	English
Abbreviated Source Title	Bull. Exp. Biol. Med.
Source	Scopus