Transformations of 1,2,4-triazines in reactions with nucleophiles: V. S-N(H) and ipso-substitution in the synthesis and transformations of 5-cyano-1,2,4-triazines / Kozhevnikov DN,Kozhevnikov VN,Kovalev IS,Rusinov VL,Chupakhin ON,Aleksandrov GG // RUSSIAN JOURNAL OF ORGANIC CHEMISTRY. - 2002. - V. 38, l. 5. - P. 744-750.

ISSN/EISSN:

1070-4280 / нет данных

Type:

Article

Abstract:

The scope of functionalization of 1,2,4-triazines can be considerably extended via successive nucleophilic substitution of hydrogen (S-N(H)) and ipso-substitution. A convenient procedure has been developed for direct cyanation of 1,2,4-triazine 4-oxides with acetone cyanohydrin in the presence of triethylamine. The cyano group in the resulting 5-cyano-1,2,4-triazines is readily replaced by reactions with various aliphatic alcohols and amines.

Author keywords:

AS-TRIAZINE DERIVATIVES; HYDROGEN

DOI:

10.1023/A:1019631610505

Web of Science ID:

ISI:000177753300021

Соавторы в МНС:

Другие поля

Поле	Значение
Month	MAY
Publisher	MAIK NAUKA/INTERPERIODICA
Address	C/O KLUWER ACADEMIC-PLENUM PUBLISHERS, 233 SPRING ST, NEW YORK, NY 10013-1578 USA
Language	English
Keywords-Plus	AS-TRIAZINE DERIVATIVES; HYDROGEN
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
ResearcherID-Numbers	Kozhevnikov, Valery/B-1178-2010
ORCID-Numbers	Kozhevnikov, Valery/0000-0001-7032-8886
Number-of-Cited-References	12
Usage-Count-Since-2013	1
Journal-ISO	Russ. J. Organ. Chem.
Doc-Delivery-Number	589HT