(beta-D-Ribofuranosyl)formamidine in the Design and Synthesis of 2-(beta-D-Ribofuranosyl)pyrimidines, Including R-F-Containing Derivatives / Iaroshenko Viktor O.,Dudkin Sergii,Sosnovskikh Vyacheslav Ya.,Villinger Alexander,Langer Peter // EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - 2013. - V. , l. 15. - P. 3166-3173.

ISSN/EISSN:

1434-193X / нет данных

Type:

Article

Abstract:

A wide range of novel 2-(beta-D-ribofuranosyl)pyrimidines, including R-F-containing derivatives, have been synthesized by the reaction of (beta-D-ribofuranosyl)formamidine with various dielectrophilic substrates such as 3-alkoxy- and 3-chloro-1-(polyfluoroalkyl)propen-1-ones, 3-nitro- and 3-(phenyl-ethynyl) chromones and heteroaryl acetylenic ketones.

Author keywords:

Nucleosides; Drug design; Drug discovery; Fluorine; Ribonucleosides; Alkynes MEDICINAL CHEMISTRY; C-NUCLEOSIDES; REGIOSELECTIVE SYNTHESIS; HETERO ANALOGS; FLUORINE; KETONES; 3-(POLYHALOACYL)CHROMONES; 3-NITROCHROMONE; TRANSFORMATION; AMINES

DOI:

10.1002/ejoc.201300107

Web of Science ID:

ISI:000320173900024

Соавторы в МНС:

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Другие поля

Поле	Значение
Month	MAY
Publisher	WILEY-V C H VERLAG GMBH
Address	BOSCHSTRASSE 12, D-69469 WEINHEIM, GERMANY
Language	English
Keywords-Plus	MEDICINAL CHEMISTRY; C-NUCLEOSIDES; REGIOSELECTIVE SYNTHESIS; HETERO ANALOGS; FLUORINE; KETONES; 3-(POLYHALOACYL)CHROMONES; 3-NITROCHROMONE; TRANSFORMATION; AMINES
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
Author-Email	viktor.iaroshenko@uni-rostock.de peter.langer@uni-rostock.de
ResearcherID-Numbers	Iaroshenko, Viktor/I-6150-2015
Number-of-Cited-References	54
Usage-Count-Since-2013	8
Journal-ISO	Eur. J. Org. Chem.
Doc-Delivery-Number	161EF