Efficient synthesis of novel thieno{[}3,2-b]-, {[}2,3-c]- and {[}3,2-c]pyridones by Sonogashira coupling of bromothiophenes with terminal alkynes and subsequent intramolecular C-N bond-forming reaction / Iaroshenko Viktor O.,Ali Sajid,Babar Tariq Mahmood,Abbasi Muhammad S. A.,Sosnovskikh Vyacheslav Ya,Villinger Alexander,Tolmachev Andrey,Langer Peter // TETRAHEDRON. - 2013. - V. 69, l. 15. - P. 3167-3181.

ISSN/EISSN:

0040-4020 / нет данных

Type:

Article

Abstract:

The coupling of bromothiophenes with terminal alkynes using triethylamine or diisopropyl amine under Sonogashira conditions (PdCl2(PPh3)(2), Cup followed by subsequent addition of amines or ammonium to the intermediate thienyl acetylenes represents a novel access to a wide range of thieno{[}3,2-b]-, {[}2,3-c]-, and {[}3,2-c]pyridones under basic conditions and in excellent yields. (C) 2013 Elsevier Ltd. All rights reserved.

Author keywords:

Sonogashira coupling; Bromothiophenes; Terminal alkynes; Thienyl acetylenes; Thieno{[}3,2-b]-; {[}2,3-c]-; and {[}3,2-c]pyridones ADHESION MOLECULE EXPRESSION; ANTIBACTERIAL ACTIVITY; THIENOPYRIDINONE ANTIBACTERIALS; HUMAN CYTOMEGALOVIRUS; CONVENIENT SYNTHESIS; 5-CARBOXYLIC ACIDS; POTENT; DERIVATIVES; INHIBITORS; RECEPTOR

DOI:

10.1016/j.tet.2013.02.069

Web of Science ID:

ISI:000316582400006

Соавторы в МНС:

—

Другие поля

Поле	Значение
Month	APR 15
Publisher	PERGAMON-ELSEVIER SCIENCE LTD
Address	THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
Language	English
Keywords-Plus	ADHESION MOLECULE EXPRESSION; ANTIBACTERIAL ACTIVITY; THIENOPYRIDINONE ANTIBACTERIALS; HUMAN CYTOMEGALOVIRUS; CONVENIENT SYNTHESIS; 5-CARBOXYLIC ACIDS; POTENT; DERIVATIVES; INHIBITORS; RECEPTOR
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
Author-Email	viktor.iaroshenko@uni-rostock.de
ResearcherID-Numbers	Iaroshenko, Viktor/I-6150-2015 ali, saqib/F-1313-2015
Number-of-Cited-References	54
Usage-Count-Since-2013	11
Journal-ISO	Tetrahedron
Doc-Delivery-Number	112HD