3-(Polyfluoroacyl)chromones and Their Hetero Analogues as Valuable Substrates for Syntheses of 4-(Polyfluoroalkyl)pyrimidines / Kotljarov Anton,Irgashev Roman A.,Iaroshenko Viktor O.,Sevenard Dmitri V.,Sosnovskikh Vyacheslav Ya // SYNTHESIS-STUTTGART. - 2009. - V. , l. 19. - P. 3233-3242.

ISSN/EISSN:

0039-7881 / нет данных

Type:

Article

Abstract:

Reactions of 3-(polyfluoroacyl)chromones and their hetero analogues with a number of 1,3-NCN-dinucleophiles, such as amidines or guanidines, were studied in detail, and preparative access to a set of diverse 5-salicyloyl-4-(polyfluoroalkyl)pyrimidines was elaborated. These compounds appear to be a suitable starting substrates for the synthesis of 4-(polyfluoroalkyl)pyrimidine-5-carboxylic acids or pyrimidines containing a benzofuran-3-yl substituent in the 5-position.

Author keywords:

chromones; thiochromones; fluorine; pyrimidine core annulation; regioselectivity; heterocycles AROMATIC METHYL KETIMINES; ONE-POT SYNTHESIS; NF-KAPPA-B; 3-SUBSTITUTED CHROMONES; CONVENIENT SYNTHESIS; FACILE SYNTHESIS; GENE-EXPRESSION; SCHIFFS BASES; PYRIMIDINES; DERIVATIVES

DOI:

10.1055/s-0029-1216957

Web of Science ID:

ISI:000270905700006

Соавторы в МНС:

Другие поля

Поле	Значение
Month	OCT 1
Publisher	GEORG THIEME VERLAG KG
Address	RUDIGERSTR 14, D-70469 STUTTGART, GERMANY
Language	English
Keywords-Plus	AROMATIC METHYL KETIMINES; ONE-POT SYNTHESIS; NF-KAPPA-B; 3-SUBSTITUTED CHROMONES; CONVENIENT SYNTHESIS; FACILE SYNTHESIS; GENE-EXPRESSION; SCHIFFS BASES; PYRIMIDINES; DERIVATIVES
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
Author-Email	yaroshenko@enamine.net
ResearcherID-Numbers	Irgashev, Roman/E-5077-2017
ORCID-Numbers	Irgashev, Roman/0000-0002-8428-1748
Funding-Acknowledgement	Russian Foundation for Basic Research {[}06-03-32388]; German Academic Exchange Service (DAAD)
Funding-Text	This work was supported financially by the Russian Foundation for Basic Research (grant 06-03-32388). The work of Anton Kotljarov was supported by the German Academic Exchange Service (DAAD).
Number-of-Cited-References	43
Usage-Count-Since-2013	5
Journal-ISO	Synthesis
Doc-Delivery-Number	508CT