First example of regioselective nucleophilic 1,6-addition of trimethyl (trifluoromethyl)silane to 4H-chromene derivatives / Sosnovskikh V. Ya.,Usachev B. I.,Permyakov M. N.,Sevenard D. V.,Roeschenthaler G.-V. // RUSSIAN CHEMICAL BULLETIN. - 2006. - V. 55, l. 9. - P. 1687-1689.

ISSN/EISSN:

1066-5285 / нет данных

Type:

Article

Abstract:

Condensation of 2-trifluoromethylchromone with diethyl malonate, ethyl cyanoacetate, and Meldrum's acid gave the corresponding methylidene derivatives of 2-trifluorometlivl-4H-chromene. Nucleophilic 1,6-addition of an excess of Me3SiCF3 in the presence of Me4NF to those obtained from the former two compounds afforded 4-substituted 2,2-bis(trifluoromethyl)-2H-chromenes.

Author keywords:

the Knoevenagel condensation; methylidene derivatives of 4H-chromene; trimethyl(trifluoromethyl)silane; nucleophilic 1,6-addition; 2,2-bis(trifluoromethyl)-2H-chromenes TRIFLUOROMETHYLATION; (TRIFLUOROMETHYL)TRIMETHYLSILANE; 2-POLYFLUOROALKYLCHROMONES; 1,4-TRIFLUOROMETHYLATION

DOI:

10.1007/s11172-006-0475-9

Web of Science ID:

ISI:000244462000029

Соавторы в МНС:

Другие поля

Поле	Значение
Month	SEP
Publisher	CONSULTANTS BUREAU/SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
Keywords-Plus	TRIFLUOROMETHYLATION; (TRIFLUOROMETHYL)TRIMETHYLSILANE; 2-POLYFLUOROALKYLCHROMONES; 1,4-TRIFLUOROMETHYLATION
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Author-Email	Vyacheslav.Sosnovskikh@usu.ru
Number-of-Cited-References	13
Usage-Count-Last-180-days	2
Usage-Count-Since-2013	8
Journal-ISO	Russ. Chem. Bull.
Doc-Delivery-Number	139VZ