2-polyfluoroalkylchromones. 10. Synthesis of regioisomeric 3-(2-hydroxyaryl)-5-polyfluoroalkyl- and 5-(2-hydroxyaryl)-3-polyfluoroalkylisoxazoles and determination of their structures by H-1, F-19, and C-13 NMR spectroscopy / Sosnovskikh VY,Sizov AY,Usachev BI // RUSSIAN CHEMICAL BULLETIN. - 2002. - V. 51, l. 7. - P. 1270-1279.

ISSN/EISSN:

1066-5285 / нет данных

Type:

Article; Proceedings Paper

Abstract:

The reactions of 2-hydroxy-2-polyfluoroalkylchroman-4-ones with hydroxylamine yield, through Delta(2)-isoxazolines as intermediate products, 3-(2-hydroxyaryl)-5-polyfluoroalkylisoxazoles. Analogous reactions with 2-polyfluoroalkylchromones afford beta-diketone monooximes, which in an acidic medium undergo cyclode hydration into 5-(2-hydroxyaryl)-3-polyfluoroalkylisoxazoles. The structures of regioisomeric 3- and 5-polyfluoroalkylisoxazoles were determined using H-1, F-19, and C-13 NMR spectroscopy.

Author keywords:

2-hydroxy-2-polyfluoroalkylchroman-4-ones, 2-polyfluoroalkylchromones, hydroxylamine hydrochloride, 5-hydroxy-5-polyfluoroalkyl-Delta(2)-isoxazolines, 5-polyfluoroalkylisoxazoles, beta-diketone monoox BETA-DIKETONES; TRIFLUOROACETONITRILE OXIDE; COUPLING-CONSTANTS; FACILE SYNTHESIS; ENOL ETHERS; HYDROXYLAMINE; HETEROCYCLES; DERIVATIVES; CHROMONES; OLEFINS

DOI:

10.1023/A:1020908831426

Web of Science ID:

ISI:000179423500025

Соавторы в МНС:

Другие поля

Поле	Значение
Month	JUL
Note	International Conference on RNA as Genomics and Therapeutic Target, NOVOSIBIRSK, RUSSIA, AUG 29-SEP 02, 2001
Publisher	CONSULTANTS BUREAU
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
Keywords-Plus	BETA-DIKETONES; TRIFLUOROACETONITRILE OXIDE; COUPLING-CONSTANTS; FACILE SYNTHESIS; ENOL ETHERS; HYDROXYLAMINE; HETEROCYCLES; DERIVATIVES; CHROMONES; OLEFINS
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Number-of-Cited-References	54
Journal-ISO	Russ. Chem. Bull.
Doc-Delivery-Number	618NE