Condensation of 2-hydroxyacetophenones with trichloroacetonitrile as a route to 2-trichloromethylchromones and 4-hydroxycoumarins / Sosnovskikh VY,Kutsenko VA,Ovsyannikov IS // RUSSIAN CHEMICAL BULLETIN. - 2000. - V. 49, l. 3. - P. 478-481.

ISSN/EISSN:

1066-5285 / нет данных

Type:

Article

Abstract:

Condensation of 2-hydroxyacetophenones with trichloroacetonitrile in the presence of N-methylanilinomagnesium bromide affords hydroxyaryl beta-amino-beta-trichloromethylvinyl ketones, which are converted into 2-trichloromethylchromones upon treatment with concentrated HCl. The resulting compounds react with alcoholic solutions of NH3 or KOH to Form 3-amino-1-(2-hydroxyaryl)-4,4,4-trichlorobut-2-en-1-ones and 4-hydroxycoumarins, respectively.

Author keywords:

2-hydroxyacetophenones; trichloroacetonitrile; 3-amino-1-(2-hydroxyaryl)-4,4,4-trichlorobut-2-en-1-ones; 2-trichloromethylchromones; 4-hydroxycoumarins

DOI:

10.1007/BF02494778

Web of Science ID:

ISI:000087951100014

Соавторы в МНС:

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Другие поля

Поле	Значение
Month	MAR
Publisher	CONSULTANTS BUREAU
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Number-of-Cited-References	20
Journal-ISO	Russ. Chem. Bull.
Doc-Delivery-Number	330FA