Synthesis of pharmacologically active hydrogels based on combined silicon and titanium polyolates / Ivanenko M. V.,Khonina T. G.,Chupakhin O. N.,Larionov L. P.,Sakhautdinova R. R.,Safronov A. P. // RUSSIAN CHEMICAL BULLETIN. - 2012. - V. 61, l. 11. - P. 2163-2171.

ISSN/EISSN:

1066-5285 / нет данных

Type:

Article

Abstract:

The target synthesis of new biologically active hydrogels based on combined silicon and titanium polyolates was carried out. The optimum conditions for hydrogel formation and their composition were determined. The type of hydrogels and mechanisms of gelation depend on the nature of polyols: gels based on combined silicon and titanium polyethylene glycolates are polymeric and formed via the polycondensation mechanism, whereas gels based on combined silicon and titanium glycerolates are colloidal and formed via the coagulation-condensation mechanism. The combined hydrogels based on silicon dimethyl glycerolates and titanium tetraglycerolate exhibit enhanced transcutaneous, wound healing, and regenerating activity.

Author keywords:

silicon and titanium polyolates; silicon-titanium hydrogels; wound healing; regenerating; transcutaneous activity MODIFIED SILANES; MONOLITHS; CHEMISTRY

DOI:

10.1007/s11172-012-0303-3

Web of Science ID:

ISI:000322877300020

Соавторы в МНС:

Другие поля

Поле	Значение
Month	NOV
Publisher	SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
Keywords-Plus	MODIFIED SILANES; MONOLITHS; CHEMISTRY
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Author-Email	mvivanenko@e1.ru
Funding-Acknowledgement	Government of the Sverdlovsk Region; Russian Foundation for Basic Research {[}10-03-96072 r\_ural\_a]; Presidium of the Russian Academy of Sciences {[}12-P-3-1030]; Ural Branch of the Russian Academy of Sciences {[}11-3-NP-666]
Funding-Text	This work was financially supported by the Government of the Sverdlovsk Region, the Russian Foundation for Basic Research (Project No. 10-03-96072 r\_ural\_a), the Presidium of the Russian Academy of Sciences, (Program No. 12-P-3-1030), and the Ural Branch of the Russian Academy of Sciences (Project No. 11-3-NP-666).
Number-of-Cited-References	29
Usage-Count-Last-180-days	2
Usage-Count-Since-2013	7
Journal-ISO	Russ. Chem. Bull.
Doc-Delivery-Number	197UP