Synthesis of fluorinated furo- and pyrrolo{[}3,4-b]quinoxaline 4,9-dioxides / Kotovskaya SK,Perova NM,Charushin VN,Chupakhin ON // MENDELEEV COMMUNICATIONS. - 1999. - V. , l. 2. - P. 76-77.

ISSN/EISSN:

0959-9436 / нет данных

Type:

Article

Abstract:

The reaction of 5,6-difluorobenzofuroxane 1 with ethyl acetoacetate in the presence of triethylamine results in the formation of 2-methyl-3-ethoxycarbonyl-6,7-difluoroquinoxaline 1,4-dioxide 2 which was converted consequently into the bromomethyl 3 and acetoxymethyl 4 derivatives; hydrolysis of the latter with hydrochloric acid gave furo{[}3,4-b]quinoxaline 4,9-dioxide 5, Compound 3 was transformed by the action of ammonia and primary alkyl amines into 2-substituted 1,3-dihydro-2H-pyrrolo{[}3,4-b]quinoxaline 4,9-dioxides 6 and further into the corresponding 6-amino compounds 7 and 8.

Author keywords:

QUINOXALINE

DOI:

нет данных

Web of Science ID:

ISI:000080179800015

Соавторы в МНС:

Другие поля

Поле	Значение
Month	MAR
Publisher	ROYAL SOC CHEMISTRY
Address	THOMAS GRAHAM HOUSE, SCIENCE PARK, MILTON RD,, CAMBRIDGE CB4 0WF, CAMBS, ENGLAND
Language	English
Keywords-Plus	QUINOXALINE
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Number-of-Cited-References	11
Journal-ISO	Mendeleev Commun.
Doc-Delivery-Number	194EU