One-step route to fluorinated furo{[}2,3-b]quinoxalines / Charushin VN,Mokrushina GA,Petrova GM,Alexandrov GG,Chupakhin ON // MENDELEEV COMMUNICATIONS. - 1998. - V. , l. 4. - P. 133-134.

ISSN/EISSN:

0959-9436 / 1364-551X

Type:

Article

Abstract:

The reaction of 6,7-difluoro-1-ethylquinoxalinium salts with 2,4-pentanedione, ethyl and bornyl acetoacetates and other beta-keto esters results in the formation of 6,7-difluoro-3a,4,9,9a-tetrahydrofuro{[}2,3-b]quinoxalines. In addition, asymmetric 6-fluoro-7-morpholino and 6-fluoro-7-thiomorpholino substituted 1-ethylquinoxalinium salts react with alkyl acetoacetates in a regio- and stereoselective manner, thus giving exclusively the corresponding alkyl 2-methyl-6-fluoro-7-substituted 3a,4,9,9a-tetrahydrofuro {[}2,3-b]quinoxalin-3-carboxylates.

Author keywords:

C-13 NMR; CYCLIZATIONS; NUCLEOPHILES; HETEROCYCLES; H-1

DOI:

нет данных

Web of Science ID:

ISI:000076183800003

Соавторы в МНС:

Другие поля

Поле	Значение
Month	JUL
Publisher	ELSEVIER SCIENCE BV
Address	PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
Language	English
EISSN	1364-551X
Keywords-Plus	C-13 NMR; CYCLIZATIONS; NUCLEOPHILES; HETEROCYCLES; H-1
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Author-Email	azine@htf.rcupi.e-burg.se
Number-of-Cited-References	9
Journal-ISO	Mendeleev Commun.
Doc-Delivery-Number	124LL