Comparative study of the iron cores in human liver ferritin, its pharmaceutical models and ferritin in chicken liver and spleen tissues using Mossbauer spectroscopy with a high velocity resolution / Alenkina I. V.,Oshtrakh M. I.,Klepova Yu. V.,Dubiel S. M.,Sadovnikov N. V.,Semionkin V. A. // SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY. - 2013. - V. 100, l. SI. - P. 88-93.

ISSN/EISSN:

1386-1425 / нет данных

Type:

Article

Abstract:

Application of Mossbauer spectroscopy with a high velocity resolution (4096 channels) for comparative analysis of iron cores in a human liver ferritin and its pharmaceutically important models Imferon, Maltofer (R) and Ferrum Lek as well as in iron storage proteins in chicken liver and spleen tissues allowed to reveal small variations in the Fe-57 hyperfine parameters related to differences in the iron core structure. Moreover, it was shown that the best fit of Mossbauer spectra of these samples required different number of components. The latter may indicate that the real iron core structure is more complex than that following from a simple core-shell model. The effect of different living conditions and age on the iron core in chicken liver was also considered. (C) 2012 Published by Elsevier B.V.

Author keywords:

Mossbauer spectroscopy with a high velocity resolution; Nanosized iron cores; Ferritin; Chicken liver and spleen; Imferon; Maltofer (R); Ferrum Lek

DOI:

10.1016/j.saa.2012.02.083

Web of Science ID:

ISI:000312181800014

Соавторы в МНС:

Другие поля

Поле	Значение
Month	JAN
Publisher	PERGAMON-ELSEVIER SCIENCE LTD
Address	THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
Language	English
Research-Areas	Spectroscopy
Web-of-Science-Categories	Spectroscopy
Author-Email	oshtrakh@mail.utnet.ru
ResearcherID-Numbers	Oshtrakh, Mikhail/L-8342-2016
ORCID-Numbers	Oshtrakh, Mikhail/0000-0002-2937-5194
Funding-Acknowledgement	Russian Foundation for Basic Research {[}09-02-00055-a]
Funding-Text	The authors wish to thank Prof. P.G. Prokopenko (The Russian State Medical University, Moscow) for the gift of the human liver ferritin and to Dr. A.L. Berkovsky (The Hematological Research Center of the RAMS, Moscow) for the help with chicken tissues lyophilization. This work was supported in part by the Russian Foundation for Basic Research (Grant \# 09-02-00055-a).
Number-of-Cited-References	19
Usage-Count-Since-2013	18
Journal-ISO	Spectroc. Acta Pt. A-Molec. Biomolec. Spectr.
Doc-Delivery-Number	052EZ