Heme iron state in various oxyhemoglobins probed using Mossbauer spectroscopy with a high velocity resolution / Oshtrakh M. I.,Berkovsky A. L.,Kumar A.,Kundu S.,Vinogradov A. V.,Konstantinova T. S.,Semionkin V. A. // BIOMETALS. - 2011. - V. 24, l. 3. - P. 501-512.

ISSN/EISSN:

0966-0844 / нет данных

Type:

Article; Proceedings Paper

Abstract:

A comparative study of oxyhemoglobins from pig, rabbit, normal human and patients with blood system malignant diseases was performed using Mossbauer spectroscopy with a high velocity resolution at 90 K. Mossbauer spectra were fitted with the help of two models: using one quadrupole doublet (model of equivalent iron electronic structure in alpha- and beta-subunits of hemoglobins) and superposition of two quadrupole doublets (model of non-equivalent iron electronic structure in alpha- and beta-subunits of hemoglobins). The results obtained using both models demonstrated small variations of hyperfine parameters that were related to the heme iron state variation in different hemoglobins. These results were compared with structural and functional differences of the hemoglobins investigated.

Author keywords:

Heme iron; Oxyhemoglobins; Mossbauer spectroscopy with a high velocity resolution; Quadrupole splitting BLOOD-OXYGEN AFFINITY; BIOMEDICAL-RESEARCH; MOLECULAR-STRUCTURE; HYPERFINE PARAMETERS; ELECTRONIC-STRUCTURE; CONTAINING PROTEINS; MODEL COMPOUNDS; HEMOGLOBIN; SPECTRA; FEATURES

DOI:

10.1007/s10534-011-9428-3

Web of Science ID:

ISI:000290448500013

Соавторы в МНС:

Другие поля

Поле	Значение
Month	JUN
Note	7th International Symposium on Biometals (Biometals 2010), Tucson, AZ, JUL 25-30, 2010
Organization	natl Inst Environm Hlth Sci; Soc Biolog Inorgan Chem; Univ Arizona Dept Chem \& Biochem \& Nutr Sci; Springer
Publisher	SPRINGER
Address	VAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS
Language	English
Keywords-Plus	BLOOD-OXYGEN AFFINITY; BIOMEDICAL-RESEARCH; MOLECULAR-STRUCTURE; HYPERFINE PARAMETERS; ELECTRONIC-STRUCTURE; CONTAINING PROTEINS; MODEL COMPOUNDS; HEMOGLOBIN; SPECTRA; FEATURES
Research-Areas	Biochemistry \& Molecular Biology
Web-of-Science-Categories	Biochemistry \& Molecular Biology
Author-Email	oshtrakh@mail.utnet.ru suman.kundu@south.du.ac.in
ResearcherID-Numbers	Oshtrakh, Mikhail/L-8342-2016
ORCID-Numbers	Oshtrakh, Mikhail/0000-0002-2937-5194
Number-of-Cited-References	41
Usage-Count-Since-2013	6
Journal-ISO	Biometals
Doc-Delivery-Number	762BY