Variation of quadrupole splitting in modified oxyhemoglobin: A Mossbauer effect study / Oshtrakh MI,Milder OB,Semionkin VA,Berkovsky AL,Azhigirova MA,Vyazova EP // ZEITSCHRIFT FUR NATURFORSCHUNG SECTION A-A JOURNAL OF PHYSICAL SCIENCES. - 2000. - V. 55, l. 1-2. - P. 193-198.

ISSN/EISSN:

0932-0784 / 1865-7109

Type:

Article; Proceedings Paper

Abstract:

Human adult hemoglobin modified by both pyridoxal-5'-phosphate and glutaraldehyde in the oxy-form was studied by Mossbauer spectroscopy. Mossbauer spectra were measured at 87 and 295 K (hemoglobin in lyophilized form) and at 87 K (hemoglobin in frozen solution). The values of the quadrupole splitting for modified oxyhemoglobin were found to be lower then those of oxyhemoglobin without modifications in lyophilized form and frozen solution, respectively. The Mossbauer spectra of modified oxyhemoglobin were also analyzed in terms of the heme iron inequivalence in alpha- and beta-subunits of the tetramer. Differences of the tendencies of temperature dependencies of quadrupole splitting for modified and non-modified oxyhemoglobin in lyophilized form were shown.

Author keywords:

hemoglobin; Mossbauer spectroscopy; quadrupole spitting HEME IRON STEREOCHEMISTRY; RED-BLOOD-CELLS; PYRIDOXYLATED HEMOGLOBIN; ELECTRONIC-STRUCTURE; GLUTARALDEHYDE; SPECTRA; FEATURES; SITE

DOI:

нет данных

Web of Science ID:

ISI:000085596200033

Соавторы в МНС:

Другие поля

Поле	Значение
Month	JAN-FEB
Note	15th International Symposium on Nuclear Quadrupole Interactions (XVth NQI 99), UNIV LEIPZIG, LEIPZIG, GERMANY, JUL 25-30, 1999
Organization	Minist Higher Educ, Res \& Culture Freestate Saxony; Bruker-Analyt GmbH
Publisher	WALTER DE GRUYTER GMBH
Address	GENTHINER STRASSE 13, D-10785 BERLIN, GERMANY
Language	English
EISSN	1865-7109
Keywords-Plus	HEME IRON STEREOCHEMISTRY; RED-BLOOD-CELLS; PYRIDOXYLATED HEMOGLOBIN; ELECTRONIC-STRUCTURE; GLUTARALDEHYDE; SPECTRA; FEATURES; SITE
Research-Areas	Chemistry; Physics
Web-of-Science-Categories	Chemistry, Physical; Physics, Multidisciplinary
Author-Email	oshtrakh@mail.utnet.ru
ResearcherID-Numbers	Oshtrakh, Mikhail/L-8342-2016
ORCID-Numbers	Oshtrakh, Mikhail/0000-0002-2937-5194
Number-of-Cited-References	24
Journal-ISO	Z. Naturfors. Sect. A-J. Phys. Sci.
Doc-Delivery-Number	289AB