Microwave-Assisted Synthesis of Fused 3-Thiocarbamoylquinolines by Reinhoudt Reaction and their Modification by Hantzsch Reaction / Platonova A. Yu.,Poluikova A. A.,Trofimova O. A.,Glukhareva T. V.,Morzherin Yu. Yu. // CHEMISTRY OF HETEROCYCLIC COMPOUNDS. - 2015. - V. 50, l. 10. - P. 1450-1456.

ISSN/EISSN:

0009-3122 / 1573-8353

Type:

Article

Abstract:

We have shown that the reaction of 2-dialkylaminobenzaldehydes with cyanothioacetamide leading to Knoevenagel condensation products and their cyclization according to tert-amino effect mechanism, may be significantly accelerated by using a microwave reactor. The synthesized tetrahydroquinolinD3/4-3-carbothioamides reacted with alpha-bromoacetophenone in microwave reactor to give 3-(1,3-thiazol-2-yl)tetrahydroquinolines.

Author keywords:

quinolines; thiazoles; thioamides; Hantzsch reaction; Knoevenagel condensation; Reinhoudt reaction; tert-amino effect; microwave irradiation RING-CLOSURE REACTIONS; HETEROCYCLIC CHEMISTRY; AMINO; CYCLIZATION; DERIVATIVES

DOI:

10.1007/s10593-014-1609-x

Web of Science ID:

ISI:000348348000009

Соавторы в МНС:

Другие поля

Поле	Значение
Month	JAN
Publisher	SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
EISSN	1573-8353
Keywords-Plus	RING-CLOSURE REACTIONS; HETEROCYCLIC CHEMISTRY; AMINO; CYCLIZATION; DERIVATIVES
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
Author-Email	yu.yu.morzherin@urfu.ru
ResearcherID-Numbers	Morzherin, Yury/M-7420-2013 Glukhareva, Tatiana/A-4610-2016
ORCID-Numbers	Morzherin, Yury/0000-0002-1333-6676 Glukhareva, Tatiana/0000-0002-5231-9879
Number-of-Cited-References	16
Usage-Count-Last-180-days	2
Usage-Count-Since-2013	17
Journal-ISO	Chem. Heterocycl. Compds.
Doc-Delivery-Number	AZ6RX