1,2,3-Thiadiazolyl Isocyanates in the Synthesis of Biologically Active Compounds. Study of the Cytotoxic Activity of N-(4-methyl-1,2,3-thiadi-azolyl-5-yl)-N'-(4-methylphenyl)Urea / Kalinina T. A.,Shakhmina Yu. S.,Glukhareva T. V.,Morzherin Yu. Yu.,Fan Z. -J.,Borzenkova R. A.,Skolobanova E. S.,Kiseleva I. S. // CHEMISTRY OF HETEROCYCLIC COMPOUNDS. - 2014. - V. 50, l. 7. - P. 1039-1046.

ISSN/EISSN:

0009-3122 / 1573-8353

Type:

Article

Abstract:

A simple method is proposed for the synthesis of 1,2,3-thiadiazolylureas by the reaction of 1,2,3-thia-diazolyl isocyanates with primary amines. 1,2,3-Thiadiazolyl isocyanates were obtained in situ by the Curtius rearrangement of 1,2,3-thiadiazolylcarbonyl azides. Cytokinin activity was tested for N-(4-methyl-1,2,3-thiadiazol-5-yl)-N'-(4-methylphenyl)urea, which is an analog of thidiazuron, differing in the presence of two methyl groups in the molecule.

Author keywords:

6-benzylaminopurine; cytokinin; isocyanates; 1,2,3-thiadiazole; thidiazuron; ureas SYSTEMIC ACQUIRED-RESISTANCE; CUCUMBER COTYLEDONS; CYTOKININ; DERIVATIVES; ARABIDOPSIS; MOIETY

DOI:

10.1007/s10593-014-1561-9

Web of Science ID:

ISI:000344092000016

Соавторы в МНС:

Другие поля

Поле	Значение
Month	OCT
Publisher	SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
EISSN	1573-8353
Keywords-Plus	SYSTEMIC ACQUIRED-RESISTANCE; CUCUMBER COTYLEDONS; CYTOKININ; DERIVATIVES; ARABIDOPSIS; MOIETY
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
Author-Email	yu.yu.morzherin@urfu.ru fanzj@nankai.edu.cn
ResearcherID-Numbers	Kiseleva, Irina/E-2902-2015 Morzherin, Yury/M-7420-2013 Glukhareva, Tatiana/A-4610-2016
ORCID-Numbers	Kiseleva, Irina/0000-0002-8709-5203 Morzherin, Yury/0000-0002-1333-6676 Glukhareva, Tatiana/0000-0002-5231-9879
Funding-Acknowledgement	Russian Foundation for Basic Research {[}13-03-00137 A]
Funding-Text	This work was carried out with the financial support of the Russian Foundation for Basic Research (grant 13-03-00137 A).
Number-of-Cited-References	32
Usage-Count-Last-180-days	1
Usage-Count-Since-2013	32
Journal-ISO	Chem. Heterocycl. Compds.
Doc-Delivery-Number	AS2EG