Synthesis of new 5-aza-isosteres of guanine containing aryl and hetaryl substituents on the 1,2,4-triazole ring / Zavodskaya Anna V.,Bakharev Vladimir V.,Parfenov Victor E.,Gidaspov Alexander A.,Slepukhin Pavel A.,Isenov Maksim L.,Eltsov Oleg S. // TETRAHEDRON LETTERS. - 2015. - V. 56, l. 9. - P. 1103-1106.

ISSN/EISSN:

0040-4039 / нет данных

Type:

Article

Abstract:

The oxidative cyclization of 4-amino-substituted 6-arylidene(hetarylmethylidene)hydrazinyl-1,3,5-triazin-2-ones with lead(IV) tetraacetate proceeds via a Dimroth-type rearrangement to give 5-amino-substituted 2-aryl(hetaryl)-1,2,4-triazolo{[}1,5-a]-1,3,5-triazin-7-ones. IR, NMR, and X-ray studies have shown that the only products of the reactions were the {[}1,5-a]-isomers. (C) 2015 Elsevier Ltd. All rights reserved.

Author keywords:

Nitrogen heterocycles; Cyclization; Fused-ring systems; Tautomerism; Rearrangement ADENOSINE A(2A) RECEPTOR; ANTI-THYMIDINE PHOSPHORYLASE; PIPERAZINE DERIVATIVES; HETEROCYCLIC-COMPOUNDS; STRUCTURE ELUCIDATION; CONVENIENT SYNTHESIS; BIOLOGICAL-ACTIVITY; N2-C3 BOND; ANTAGONISTS; POTENT

DOI:

10.1016/j.tetlet.2015.01.151

Web of Science ID:

ISI:000350087800013

Соавторы в МНС:

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Другие поля

Поле	Значение
Month	FEB 25
Publisher	PERGAMON-ELSEVIER SCIENCE LTD
Address	THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
Language	English
Keywords-Plus	ADENOSINE A(2A) RECEPTOR; ANTI-THYMIDINE PHOSPHORYLASE; PIPERAZINE DERIVATIVES; HETEROCYCLIC-COMPOUNDS; STRUCTURE ELUCIDATION; CONVENIENT SYNTHESIS; BIOLOGICAL-ACTIVITY; N2-C3 BOND; ANTAGONISTS; POTENT
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
Author-Email	parfenovve@gmail.com
ResearcherID-Numbers	Parfenov, Victor/D-7902-2014
ORCID-Numbers	Parfenov, Victor/0000-0002-0079-5670
Funding-Acknowledgement	Ministry of Education and Science of Russia within the scope of the project section of the State task for the Samara State Technical University {[}4.813.2014/K]
Funding-Text	This research was supported by the Ministry of Education and Science of Russia within the scope of the project section of the State task for the Samara State Technical University (project No. 4.813.2014/K).
Number-of-Cited-References	61
Usage-Count-Since-2013	10
Journal-ISO	Tetrahedron Lett.
Doc-Delivery-Number	CC1FY