Synthesis of novel derivatives of 2-(azolylimino)thiazoline / Eltsov OS,Mokrushin VS,Tkachev AV // RUSSIAN CHEMICAL BULLETIN. - 2004. - V. 53, l. 10. - P. 2293-2302.

ISSN/EISSN:

1066-5285 / нет данных

Type:

Article

Abstract:

Successive alkylation of 5-(3-phenylthioureido)-3H-imidazole-4-carboxamides with alkyl halides and chloroacetone gave (N-oxopropylimidazolyl)isothioureas, which were easily converted into derivatives of purine and imidazopyrazinone. In the case of ethyl 5-(3-phenylthioureido)-3H-imidazole-4-carboxylate, primary alkylation occurs at the N atom of the imidazole ring. Reactions of 5-(3-phenylthioureido)-3H-imidazole-4-carboxamides with halo-ketones afforded a number of 4-hydroxy-2-imidazolyliminothiazolidines and 2-imidazolylimino-Delta(4)-thiazolines.

Author keywords:

haloketone; alkylation; 2-imidazolylimino-Delta(4)-thiazolines; imidazo{[}5,1-c]pyrazin-7-ones; imidazolylthiourea; purine derivatives; alkyl halides; (N-alkylimidazolyl)isothioureas

DOI:

10.1007/s11172-005-0116-8

Web of Science ID:

ISI:000227891300038

Соавторы в МНС:

Другие поля

Поле	Значение
Month	OCT
Publisher	CONSULTANTS BUREAU
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Author-Email	eltsov@htf.ustu.ru atkachev@nioch.nsc.ru
Number-of-Cited-References	11
Usage-Count-Since-2013	1
Journal-ISO	Russ. Chem. Bull.
Doc-Delivery-Number	909WL