A concise approach to CF3-containing furan-3-ones, (bis)pyrazoles from novel fluorinated building blocks based on 2,3-butanedione / Bazhin Denis N.,Chizhov Dmitry L.,Roeschenthaler Gerd-Volker,Kudyakova Yulia S.,Burgart Yanina V.,Slepukhin Pavel A.,Saloutin Victor I.,Charushin Valery N. // TETRAHEDRON LETTERS. - 2014. - V. 55, l. 42. - P. 5714-5717.

ISSN/EISSN:

0040-4039 / нет данных

Type:

Article

Abstract:

1,1,1-Trifluoro-4,5,5-trimethoxyhex-3-en-2-one and lithium (2Z)-1,1,1-trifluoro-5,5-dialkoxy-4-oxohex2-en-2-olate were synthesized for the first time via direct trifluoroacetylation of 2,3-butanedione acetal derivatives. A simple and effective approach to acetal or acyl substituted CF3-pyrazoles, 5,5 `-bis(trifluoromethyl)-3,3 `-bipyrazole, and, to 5-trifluoromethylfuran-3-ones is presented. (C) 2014 Elsevier Ltd. All rights reserved.

Author keywords:

Claisen condensation; Trifluoroacetylation; Alkoxyenones; Furanones; Pyrazoles ORGANIC-SYNTHESIS; 1,3-DICARBONYL COMPOUNDS; DERIVATIVES; CHEMISTRY; TRIFLUOROMETHYL; HETEROCYCLES; CONVENIENT; FLUOROALKYL; PYRROLES; ACETALS

DOI:

10.1016/j.tetlet.2014.08.046

Web of Science ID:

ISI:000343344100002

Соавторы в МНС:

Другие поля

Поле	Значение
Month	OCT 15
Publisher	PERGAMON-ELSEVIER SCIENCE LTD
Address	THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
Language	English
Keywords-Plus	ORGANIC-SYNTHESIS; 1,3-DICARBONYL COMPOUNDS; DERIVATIVES; CHEMISTRY; TRIFLUOROMETHYL; HETEROCYCLES; CONVENIENT; FLUOROALKYL; PYRROLES; ACETALS
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
Author-Email	bazhin@ios.uran.ru
ResearcherID-Numbers	Kudyakova, Yulia/J-7484-2016 Bazhin, Denis/P-4667-2014 Burgart, Yanina/T-8025-2017
ORCID-Numbers	Kudyakova, Yulia/0000-0003-0637-1606 Bazhin, Denis/0000-0003-3972-6995 Burgart, Yanina/0000-0001-6061-2410
Funding-Acknowledgement	DFG (German Science Foundation) {[}RO 362/58-1]; Program of the Ural Branch of RAS {[}12-P-3-1020]; Russian Federation {[}3656.2014.3]
Funding-Text	This work was supported financially by the DFG (German Science Foundation), Grant No. RO 362/58-1, the Program of the Ural Branch of RAS (Project 12-P-3-1020), the State Program for Supporting of Leading Scientific Schools of the Russian Federation (Grant 3656.2014.3). D.N.B. is thankful to Dr. Evgeny V. Shchegol'kov for useful discussion.
Number-of-Cited-References	58
Usage-Count-Since-2013	31
Journal-ISO	Tetrahedron Lett.
Doc-Delivery-Number	AR1KM