New method for the annelation of the pyridine fragment to azines / Charushin VN,Boguslavsky AM,Ponizovsky MG,Kodess MI,Chekhlov AN,Mkoyan SG,Aldoshin SM // RUSSIAN CHEMICAL BULLETIN. - 2004. - V. 53, l. 6. - P. 1267-1271.

ISSN/EISSN:

1066-5285 / 1573-9171

Type:

Article

Abstract:

The reaction of quinoxaline-2-carbaldehyde with ethyl (E)-3-aminocrotonate afforded ethyl 4-oxo-1,4-dihydropyrido{[}2,3-b]quinoxaline-3-carboxylate, which is a structural analog of nalidixic and 4-quinolone-3-carboxylic acids representing the basis of the known antibacterial drugs of the fluoroquinolone series.

Author keywords:

S-N(H) methodology; intramolecular cyclizations; quinoxaline-2-carbaldehyde; dinucleophiles; enamino esters; 4-oxo-1H-pyrido{[}2,3-b]-quinoxaline QUINOXALINES

DOI:

10.1023/B:RUCB.0000042285.0167

Web of Science ID:

ISI:000224147800020

Соавторы в МНС:

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Другие поля

Поле	Значение
Month	JUN
Publisher	SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
EISSN	1573-9171
Keywords-Plus	QUINOXALINES
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Author-Email	charushin@htf.ustu.ru charushin@prm.uran.ru sma@icp.ac.ru
ResearcherID-Numbers	Aldoshin, Sergey/H-1647-2011
Number-of-Cited-References	16
Usage-Count-Since-2013	1
Journal-ISO	Russ. Chem. Bull.
Doc-Delivery-Number	857VR