The cardiac muscle duplex as a method to study myocardial heterogeneity / Solovyova O.,Katsnelson L. B.,Konovalov P. V.,Kursanov A. G.,Vikulova N. A.,Kohl P.,Markhasin V. S. // PROGRESS IN BIOPHYSICS \& MOLECULAR BIOLOGY. - 2014. - V. 115, l. 2-3. - P. 115-128.

ISSN/EISSN:
0079-6107 / нет данных
Type:
Review
Abstract:
This paper reviews the development and application of paired muscle preparations, called duplex, for the investigation of mechanisms and consequences of intra-myocardial electro-mechanical heterogeneity. We illustrate the utility of the underlying combined experimental and computational approach for conceptual development and integration of basic science insight with clinically relevant settings, using previously published and new data. Directions for further study are identified. (C) 2014 The Authors. Published by Elsevier Ltd.
Author keywords:
Cardiomyocyte interaction; Excitation-contraction coupling; Cardiac mechano-electric coupling; Electro-mechanical mathematical model; Cardiac tissue; Mechano-electric feedback MECHANOSENSITIVE ION CHANNELS; HUMAN LEFT-VENTRICLE; OPEN RESOURCE COR; IN-VITRO; ELECTRICAL HETEROGENEITY; TRANSMURAL HETEROGENEITY; ELECTROMECHANICAL MODEL; THEORETICAL-MODELS; REGIONAL ISCHEMIA; GENE-EXPRESSION
DOI:
10.1016/j.pbiomolbio.2014.07.0
Web of Science ID:
ISI:000344424700006
Соавторы в МНС:
Другие поля
Поле Значение
Month AUG
Publisher PERGAMON-ELSEVIER SCIENCE LTD
Address THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND
Language English
Keywords-Plus MECHANOSENSITIVE ION CHANNELS; HUMAN LEFT-VENTRICLE; OPEN RESOURCE COR; IN-VITRO; ELECTRICAL HETEROGENEITY; TRANSMURAL HETEROGENEITY; ELECTROMECHANICAL MODEL; THEORETICAL-MODELS; REGIONAL ISCHEMIA; GENE-EXPRESSION
Research-Areas Biochemistry \& Molecular Biology; Biophysics
Web-of-Science-Categories Biochemistry \& Molecular Biology; Biophysics
Author-Email o.solovyova@iip.uran.ru
ResearcherID-Numbers Konovalov, Pavel/D-9838-2015 Balakina-Vikulova, Nathalie/D-9833-2015 Solovyova, Olga/T-8232-2017 Kursanov, Alexander/A-4003-2015
ORCID-Numbers Balakina-Vikulova, Nathalie/0000-0003-1316-4437 Kursanov, Alexander/0000-0002-0563-0808 Kohl, Peter/0000-0003-0416-6270
Funding-Acknowledgement Ural Branch of the RAS {[}12-M-14-2009, 12-Pi-4-1067]; Programme of Basic Research of the Presidium of RAS, Ural Federal University {[}211]; Russian Foundation for Basic Research {[}14-01-31134, 14-01-00885]; European Research Council Advanced Grant (CardioNect)
Funding-Text The authors gratefully acknowledge the kind help of Mrs. Katherine Fletcher with careful revision of the text, and research support from the Ural Branch of the RAS (12-M-14-2009, 12-Pi-4-1067), Programme \#1 of Basic Research of the Presidium of RAS, Ural Federal University (No.211 Decree of the Government of RF of 16th March 2013), and the Russian Foundation for Basic Research (14-01-31134, 14-01-00885). PK is a Senior Research Fellow of the British Heart Foundation and supported by a European Research Council Advanced Grant (CardioNect).
Number-of-Cited-References 102
Usage-Count-Since-2013 9
Journal-ISO Prog. Biophys. Mol. Biol.
Doc-Delivery-Number AS7GI