Electron-conformational transformations in nanoscopic RyR channels governing both the heart's contraction and beating / Moskvin A. S.,Ryvkin A. M.,Solovyova O. E.,Markhasin V. S. // JETP LETTERS. - 2011. - V. 93, l. 7. - P. 403-408.

ISSN/EISSN:

0021-3640 / нет данных

Type:

Article

Abstract:

We show that a simple biophysically based electron-conformational model of RyR channel can explain and describe on equal footing the oscillatory regime of the heart's cell release unit both in sinoatrial node (pacemaker) cells under normal physiological conditions and in ventricular myocytes under Ca2+ sarcoplasmic reticulum overload.

Author keywords:

MATHEMATICAL-MODEL; CA2+; PACEMAKING; DYNAMICS; CELLS

DOI:

10.1134/S0021364011070083

Web of Science ID:

ISI:000291361400009

Соавторы в МНС:

Другие поля

Поле	Значение
Month	JUN
Publisher	MAIK NAUKA/INTERPERIODICA/SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013-1578 USA
Language	English
Keywords-Plus	MATHEMATICAL-MODEL; CA2+; PACEMAKING; DYNAMICS; CELLS
Research-Areas	Physics
Web-of-Science-Categories	Physics, Multidisciplinary
Author-Email	alexandr.moskvin@usu.ru
ResearcherID-Numbers	Solovyova, Olga/T-8232-2017
Funding-Acknowledgement	Ural Branch, Russian Academy of Sciences {[}09-M-14-2001]
Funding-Text	This work was supported by the Ural Branch, Russian Academy of Sciences, project no. 09-M-14-2001.
Number-of-Cited-References	16
Usage-Count-Last-180-days	1
Usage-Count-Since-2013	14
Journal-ISO	Jetp Lett.
Doc-Delivery-Number	774DL