Models of active transport of neurotransmitters in synaptic vesicles / Melkikh Alexey V.,Seleznev Vladimir D. // JOURNAL OF THEORETICAL BIOLOGY. - 2007. - V. 248, l. 2. - P. 350-353.

ISSN/EISSN:

0022-5193 / нет данных

Type:

Article

Abstract:

Models of the active transport of neurotransmitters in synaptic vesicles were constructed. The models were used to determine the resting potential at membranes of synaptic vesicles: 40 mV (monoamines and acetylcholine) and -40 mV (glutamate). The potential at the membrane of a synaptic vesicle was almost absent for the transport of GABA and glycine. The neurotransmitter concentration of a cell was 0.1-18mM at the concentration of neurotransmitters in a vesicle equal to 0.5M. This result is in qualitative agreement with the relevant experimental data. (c) 2007 Elsevier Ltd. All rights reserved.

Author keywords:

synaptic vesicles; active transport of neurotransmitters; resting potential GLUTAMATE TRANSPORT; GRADIENT; BIOMEMBRANES; MEMBRANE; IONS; PH

DOI:

10.1016/j.jtbi.2007.05.022

Web of Science ID:

ISI:000249611200014

Соавторы в МНС:

Другие поля

Поле	Значение
Month	SEP 21
Publisher	ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD
Address	24-28 OVAL RD, LONDON NW1 7DX, ENGLAND
Language	English
Keywords-Plus	GLUTAMATE TRANSPORT; GRADIENT; BIOMEMBRANES; MEMBRANE; IONS; PH
Research-Areas	Life Sciences \& Biomedicine - Other Topics; Mathematical \& Computational Biology
Web-of-Science-Categories	Biology; Mathematical \& Computational Biology
Author-Email	mav@dpt.ustu.ru
Number-of-Cited-References	11
Usage-Count-Since-2013	4
Journal-ISO	J. Theor. Biol.
Doc-Delivery-Number	212QF