Requirements on models and models of active transport of ions in biomembranes / Melkikh AV,Seleznev VD // BULLETIN OF MATHEMATICAL BIOLOGY. - 2006. - V. 68, l. 2. - P. 385-399.

ISSN/EISSN:

0092-8240 / нет данных

Type:

Article

Abstract:

Requirements on models of the active transport of ions in biomembranes have been formulated. The basic requirements include an explicit dependence of the resting potential and intracellular concentrations of ions on the difference of ATP-ADP chemical potentials, a consideration of the reversibility of the ionic pump operation. a correlation between theoretical and experimental data on the resting potential and intracellular concentrations of ions for different types of cells, the pump efficiency approaching 100\%, and a tendency of the resting potential to the Donnan potential if the active transport is blocked. A model satisfying the aforementioned requirements has been proposed by the authors as an example.

Author keywords:

active transport of ions; resting potential; reversibility of ionic pumps; conformon VOLTAGE-DEPENDENCE; CARDIAC MYOCYTES; PUMP; MOTORS

DOI:

10.1007/s11538-005-9035-y

Web of Science ID:

ISI:000237958300009

Соавторы в МНС:

Другие поля

Поле	Значение
Month	FEB
Publisher	ACADEMIC PRESS LTD ELSEVIER SCIENCE LTD
Address	24-28 OVAL RD, LONDON NW1 7DX, ENGLAND
Language	English
Keywords-Plus	VOLTAGE-DEPENDENCE; CARDIAC MYOCYTES; PUMP; MOTORS
Research-Areas	Life Sciences \& Biomedicine - Other Topics; Mathematical \& Computational Biology
Web-of-Science-Categories	Biology; Mathematical \& Computational Biology
Author-Email	mav@dpt.ustu.ru
Number-of-Cited-References	24
Usage-Count-Since-2013	1
Journal-ISO	Bull. Math. Biol.
Doc-Delivery-Number	048PF