Interaction of 3,8-Disubstituted Imidazo-{[}5,1-C]{[}1,2,4]Triazines with Nucleophiles / Sadchikova E. V.,Mokrushin V. S. // CHEMISTRY OF HETEROCYCLIC COMPOUNDS. - 2014. - V. 50, l. 7. - P. 1014-1020.

ISSN/EISSN:

0009-3122 / 1573-8353

Type:

Article

Abstract:

We studied the reactivity of diethyl 4-aminoimidazo{[}5,1-N]{[}1,2,4]triazine-3,8-dicarboxylate in reactions with nucleophiles and demonstrated the possibility of selective formation of monoamides by interaction with primary and secondary aliphatic amines. It was determined that the carbon atom at position 4 of imidazo{[}1,5-N]{[}1,2,4]triazine system underwent nucleophilic attack, enabling the synthesis of imidazo-{[}1',5':3,4]{[}1,2,4]triazino{[}5,6-b]{[}1,5]benzoxazepines and imidazo{[}1',5':3,4]{[}1,2,4]triazino{[}5,6-b]{[}1,5]benzo- diazepines, as well as (pyrazol-4-ylidenehydrazino)imidazoles, depending on the bisnucleophile used.

Author keywords:

diazepines; imidazolylhydrazones; imidazotriazines; oxazepines; polycondensed heterocyclic systems

DOI:

10.1007/s10593-014-1557-5

Web of Science ID:

ISI:000344092000012

Соавторы в МНС:

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Другие поля

Поле	Значение
Month	OCT
Publisher	SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
EISSN	1573-8353
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
Author-Email	selena-ekb@rambler.ru
Funding-Acknowledgement	Russian Foundation for Basic Research {[}14-03-01033]
Funding-Text	The work was performed with financial support from the Russian Foundation for Basic Research (project 14-03-01033).
Number-of-Cited-References	6
Usage-Count-Since-2013	2
Journal-ISO	Chem. Heterocycl. Compds.
Doc-Delivery-Number	AS2EG