New synthesis of 1,4-benzothiazepin-5-ones / Mironov MA,Ivantsova MN,Tokareva MI,Mokrushin VS // RUSSIAN CHEMICAL BULLETIN. - 2004. - V. 53, l. 6. - P. 1232-1236.

ISSN/EISSN:

1066-5285 / 1573-9171

Type:

Article

Abstract:

A new convenient method for the synthesis of 1,4 -benzothiazepin-5-ones by a one-pot procedure including condensation of thiosalicylic acid with chloroacetone and the reaction of the resulting 2-(acetoxythio)benzoic acid without isolation with primary amines and isocyanides is proposed. This method can be used for the combinatorial search of compounds with biological activities in the 1,4-benzothiazepine series.

Author keywords:

Ugi reaction; isocyanides; 1,4-benzothiazepines; combinatorial synthesis SOLID-PHASE SYNTHESIS; DERIVATIVES

DOI:

10.1023/B:RUCB.0000042278.1469

Web of Science ID:

ISI:000224147800013

Соавторы в МНС:

Другие поля

Поле	Значение
Month	JUN
Publisher	SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
EISSN	1573-9171
Keywords-Plus	SOLID-PHASE SYNTHESIS; DERIVATIVES
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Author-Email	mir@htf.ustu.ru
ResearcherID-Numbers	Ivantsova, Maria/R-5878-2016
ORCID-Numbers	Ivantsova, Maria/0000-0002-2389-0523
Number-of-Cited-References	13
Usage-Count-Last-180-days	3
Usage-Count-Since-2013	8
Journal-ISO	Russ. Chem. Bull.
Doc-Delivery-Number	857VR