Synthesis and Tuberculostatic Activity of Some 1,2,4-Triazines / Shchegol'kov E. V.,Khudina O. G.,Ivanova A. E.,Burgart Ya. V.,Sadchikova E. V.,Kravchenko M. A.,Saloutin V. I. // PHARMACEUTICAL CHEMISTRY JOURNAL. - 2014. - V. 48, l. 6. - P. 383-386.

ISSN/EISSN:

0091-150X / 1573-9031

Type:

Article

Abstract:

The antituberculosis activity of dihydrotriazolo{[}5,1-c]{[}1,2,4]triazines, dihydropyrazolo{[}5,1-c]{[}1,2,4]triazines, dihydroimidazolo{[}5,1-c]{[}1,2,4]triazines, and dihydrotetrazolo{[}5,1-c]{[}1,2,4]triazines was studied. A synthetic method for convenient synthons, 3-amino-1,2,4-triazines, was proposed. Their tuberculostatic activity was investigated.

Author keywords:

antituberculosis activity; 1,2,4-triazines; synthesis ANTIMICROBIAL ACTIVITY; DERIVATIVES; MOIETY; THIAZOLE

DOI:

10.1007/s11094-014-1115-6

Web of Science ID:

ISI:000344002400006

Соавторы в МНС:

Другие поля

Поле	Значение
Month	SEP
Publisher	SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
EISSN	1573-9031
Keywords-Plus	ANTIMICROBIAL ACTIVITY; DERIVATIVES; MOIETY; THIAZOLE
Research-Areas	Pharmacology \& Pharmacy
Web-of-Science-Categories	Chemistry, Medicinal; Pharmacology \& Pharmacy
ResearcherID-Numbers	Shchegol'kov, Evgenii/H-6790-2015 Burgart, Yanina/T-8025-2017
ORCID-Numbers	Shchegol'kov, Evgenii/0000-0001-6611-2855 Burgart, Yanina/0000-0001-6061-2410
Funding-Acknowledgement	UrB, RAS {[}12-P-1030]; RF President Committee on Grants {[}NSh-3656.2014.3]; Russian Foundation for Basic Research {[}13-03-00617]
Funding-Text	The work was supported financially by the UrB, RAS (Project 12-P-1030), the RF President Committee on Grants (Grant NSh-3656.2014.3), and the Russian Foundation for Basic Research (Grant 13-03-00617).
Number-of-Cited-References	27
Usage-Count-Since-2013	11
Journal-ISO	Pharm. Chem. J.
Doc-Delivery-Number	AS0YK