Synthesis and structure of 2-ethoxy- and 2-aminomethylidene-3-fluoroalkyl-3-oxopropionates / Pryadeina M. V.,Burgart Ya. V.,Saloutin V. I.,Slepukhin P. A.,Kazheva O. N.,Shilov G. V.,D'yachenko O. A.,Chupakhin O. N. // RUSSIAN JOURNAL OF ORGANIC CHEMISTRY. - 2007. - V. 43, l. 7. - P. 945-955.

ISSN/EISSN:

1070-4280 / нет данных

Type:

Article

Abstract:

Condensation of ethyl 3-polyfluoroalkyl-3-oxopropionates with excess triethyl orthoformate gave ethyl 3-polyfluoroalkyl-2-ethoxymethylidene-3-oxopropionates which reacted with primary aliphatic, aromatic, and heterocyclic amines to form ethyl 2-alkyl(aryl, hetaryl)aminomethylidene-3-polyfluoroalkyl-3-oxopropionates. According to the X-ray diffraction and IR data, the latter exist in the crystalline state as the corresponding E isomers, while in solution (NMR data), as mixtures of Z and E isomers. Condensation of ethyl 2-ethoxymethylidene-3-oxopropionates with secondary heterocyclic amines (morpholine and pyrrolidine) led to the formation of 2-morpholino(pyrrolidin-1-yl)methylidene-3-fluoroalkyl-3-oxopropionates which were shown to exist as Z isomers both in the crystalline state and in solution.

Author keywords:

нет данных

DOI:

10.1134/S1070428007070019

Web of Science ID:

ISI:000248827900001

Соавторы в МНС:

Другие поля

Поле	Значение
Month	JUL
Publisher	MAIK NAUKA/INTERPERIODICA/SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013-1578 USA
Language	English
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
Author-Email	saloutin@ios.uran.ru
ResearcherID-Numbers	Burgart, Yanina/T-8025-2017
ORCID-Numbers	Burgart, Yanina/0000-0001-6061-2410
Number-of-Cited-References	15
Usage-Count-Last-180-days	1
Usage-Count-Since-2013	4
Journal-ISO	Russ. J. Organ. Chem.
Doc-Delivery-Number	201JR