Reactions of 5,6,7,8-tetrafluoro-4-hydroxycoumarin derivatives with benzylamine and aniline / Shcherbakov K. V.,Burgart Ya. V.,Saloutin V. I. // RUSSIAN CHEMICAL BULLETIN. - 2006. - V. 55, l. 7. - P. 1215-1219.

ISSN/EISSN:

1066-5285 / нет данных

Type:

Article

Abstract:

5,6,7,8-Tetrafluoro-4-hydroxycoumarin reacted with benzylamine under mild conditions to give a stable salt, while its refluxing with aniline or benzylamine in xylene afforded 5,6,7,8-tetrafluoro-4-phenyl(benzyl)aminocoumarins. Reactions of 3-acetyl(acetimidoyl)5,6,7,8-tetrafluoro-4-hydroxycoumarins with benzylamine followed different pathways, depending on the solvent. Condensation at the acyl substituent can be accompanied by replacement of the F atom in position 7. 3-Acetylcoumarin formed a salt, while 3-acetimidoylcoumarin yielded a 7-monosubstituted product. 3-Acetyl(acetimidoyl)-5,6,7,8-tetrafluoro-4-hydroxycoumarins reacted with aniline to give only 5,6,7,8-tetrafluoro-4-hydroxy-3-(N-phenylacetimidoyl)coumarin.

Author keywords:

coumarins; amines; organofluorine compounds; nucleophilic substitution N-NUCLEOPHILES

DOI:

10.1007/s11172-006-0401-1

Web of Science ID:

ISI:000242918900017

Соавторы в МНС:

Другие поля

Поле	Значение
Month	JUL
Publisher	CONSULTANTS BUREAU/SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013 USA
Language	English
Keywords-Plus	N-NUCLEOPHILES
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Multidisciplinary
Author-Email	saloutin@ios.uran.ru
ResearcherID-Numbers	Burgart, Yanina/T-8025-2017
ORCID-Numbers	Burgart, Yanina/0000-0001-6061-2410
Number-of-Cited-References	9
Journal-ISO	Russ. Chem. Bull.
Doc-Delivery-Number	118CF