Synthesis of fluorine-containing 2-(1-aryl-4-oxo-1,4-dihydrocinnolin-3-yl)-2-oxoacetic acids / Fokin A. S.,Burgart Ya. V.,Saloutin V. I.,Chupakhin O. N. // RUSSIAN JOURNAL OF ORGANIC CHEMISTRY. - 2005. - V. 41, l. 9. - P. 1374-1376.

ISSN/EISSN:

1070-4280 / нет данных

Type:

Article

Abstract:

Acid hydrolysis of ethyl 2-(1-aryl-5,6,7,8-tetrafluoro-4-oxo-1,4-dihydrocinnolin-3-yl)-2-oxoaceta tes gives 2-(1-aryl-5,6,7,8-tetrafluoro-4-oxo-1,4-dihydrocinnolin-3-yl)-2,2-dihydr oxyacetic acids which undergo dehydration on heating in toluene to afford 2-(1-aryl-5,6,7,8-tetrafluoro-4-oxo-1,4-dihydrocinnolin-3yl)-2-oxoacetic acids. Reactions of the latter with excess morpholine result in replacement of two fluorine atoms in positions 5 and 7 by the amine residues.

Author keywords:

нет данных

DOI:

10.1007/s11178-005-0349-x

Web of Science ID:

ISI:000202967700020

Соавторы в МНС:

Другие поля

Поле	Значение
Month	SEP
Publisher	MAIK NAUKA/INTERPERIODICA/SPRINGER
Address	233 SPRING ST, NEW YORK, NY 10013-1578 USA
Language	English
Research-Areas	Chemistry
Web-of-Science-Categories	Chemistry, Organic
Author-Email	saloutin@ios.uran.ru
ResearcherID-Numbers	Burgart, Yanina/T-8025-2017
ORCID-Numbers	Burgart, Yanina/0000-0001-6061-2410
Number-of-Cited-References	11
Usage-Count-Last-180-days	1
Usage-Count-Since-2013	1
Journal-ISO	Russ. J. Organ. Chem.
Doc-Delivery-Number	V43XL